Long-acting microneedle formulations

LK Vora, AH Sabri, Y Naser, A Himawan… - Advanced Drug Delivery …, 2023 - Elsevier
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …

Microneedles as a momentous platform for psoriasis therapy and diagnosis: A state-of-the-art review

BHJ Gowda, MG Ahmed, U Hani, P Kesharwani… - International Journal of …, 2023 - Elsevier
Psoriasis is a chronic, autoimmune, and non-communicable skin disease with a worldwide
prevalence rate of 2–3%, creating an economic burden on global health. Some significant …

[HTML][HTML] Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer

H Abd-El-Azim, IA Tekko, A Ali, A Ramadan… - Journal of Controlled …, 2022 - Elsevier
Photodynamic therapy (PDT) to manage non-melanoma skin cancers has garnered great
attention over the past few years. Hypericin (Hy) is a potent lipid-soluble photosensitiser with …

[HTML][HTML] Design and fabrication of customizable microneedles enabled by 3D printing for biomedical applications

JM Loh, YJL Lim, JT Tay, HM Cheng, HL Tey, K Liang - Bioactive Materials, 2024 - Elsevier
Microneedles (MNs) is an emerging technology that employs needles ranging from 10 to
1000 μm in height, as a minimally invasive technique for various procedures such as …

[HTML][HTML] Liposome-loaded polymeric microneedles for enhanced skin deposition of rifampicin

QK Anjani, AK Pandya, S Demartis… - International Journal of …, 2023 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is a prevailing bacterial pathogen
linked to superficial skin and soft tissue infections (SSTIs). Rifampicin (RIF), a potent …

[HTML][HTML] Ring inserts as a useful strategy to prepare tip-loaded microneedles for long-acting drug delivery with application in HIV pre-exposure prophylaxis

AJ Paredes, AD Permana, F Volpe-Zanutto, MN Amir… - Materials & …, 2022 - Elsevier
The role of microneedle array patches (MAPs) and, in particular, dissolving MAPs in
transdermal drug delivery has increased exponentially over the last decade. MAPs are able …

Microneedle‐assisted transdermal delivery of nanoparticles: Recent insights and prospects

AJ Guillot, M Martínez‐Navarrete… - Wiley …, 2023 - Wiley Online Library
Transdermal delivery of drugs offers an interesting alternative for the administration of
molecules that present certain troubles when delivered by the oral route. It can produce …

[HTML][HTML] MAP-box: a novel, low-cost and easy-to-fabricate 3D-printed box for the storage and transportation of dissolving microneedle array patches

QK Anjani, Á Cárcamo-Martínez, LAH Wardoyo… - Drug Delivery and …, 2024 - Springer
Research on the use of microarray patches (MAPs) has progressed at an unprecedented
rate over the years, leading to the development of many novel drug delivery systems. As the …

Nanosuspension-loaded dissolving bilayer microneedles for hydrophobic drug delivery to the posterior segment of the eye

Y Wu, LK Vora, D Mishra, MF Adrianto, S Gade… - Biomaterials …, 2022 - Elsevier
Intravitreal injections (IVT) are regarded as the gold standard for effective delivery of
hydrophobic drugs to the back of the eye. However, as a highly invasive procedure, the …

[HTML][HTML] Metronidazole nanosuspension loaded dissolving microarray patches: An engineered composite pharmaceutical system for the treatment of skin and soft …

QK Anjani, AHB Sabri, J Domínguez-Robles… - Biomaterials …, 2022 - Elsevier
Bacteroides fragilis is one of the most common causative group of microorganisms that is
associated with skin and soft tissue infections (SSTI). Metronidazole (MTZ) is the drug of …