Role of alternative splicing in sex determination in vertebrates

I Gómez-Redondo, B Planells, P Navarrete… - Sexual …, 2021 - karger.com
During the process of sex determination, a germ-cell-containing undifferentiated gonad is
converted into either a male or a female reproductive organ. Both the composition of sex …

Hatching is modulated by microRNA-378a-3p derived from extracellular vesicles secreted by blastocysts

KC Pavani, T Meese, OB Pascottini… - Proceedings of the …, 2022 - National Acad Sciences
Extracellular vesicles (EVs) and their cargo microRNAs (miRNAs) are important regulators of
embryo development to the blastocyst stage and beyond. Before implantation can take …

Extracellular vesicles, microRNA and the preimplantation embryo: non-invasive clues of embryo well-being

DC Hawke, AJ Watson, DH Betts - Reproductive BioMedicine Online, 2021 - Elsevier
Elective single embryo transfer is rapidly becoming the standard of care in assisted
reproductive technology for patients under the age of 35 years with a good prognosis …

[HTML][HTML] MicroRNAs from extracellular vesicles secreted by bovine embryos as early biomarkers of developmental competence

B Melo-Baez, YS Wong, CJ Aguilera… - International journal of …, 2020 - mdpi.com
During early development, embryos secrete extracellular vesicles (EVs) that participate in
embryo–maternal communication. Among other molecules, EVs carry microRNAs (miRNAs) …

Extracellular vesicles secreted during blastulation show viability of bovine embryos

EA Mellisho, MA Briones, AE Velásquez… - …, 2019 - rep.bioscientifica.com
Extracellular vesicles (EVs) secreted by blastocysts may be clinically relevant, as indicator of
embryo viability on in vitro fertilization. We tested if the characteristics of extracellular …

[HTML][HTML] Murine blastocysts release mature MicroRNAs into culture media that reflect developmental status

DC Hawke, DB Ahmed, AJ Watson, DH Betts - Frontiers in Genetics, 2021 - frontiersin.org
Extracellular microRNA (miRNA) sequences derived from the pre-implantation embryo have
attracted interest for their possible contributions to the ongoing embryonic–uterine milieu, as …

[HTML][HTML] MicroRNA-148b secreted by bovine oviductal extracellular vesicles enhance embryo quality through BPM/TGF-beta pathway

K Cañón-Beltrán, YN Cajas, V Almpanis, SG Egido… - Biological Research, 2024 - Springer
Abstract Background Extracellular vesicles (EVs) and their cargoes, including MicroRNAs
(miRNAs) play a crucial role in cell-to-cell communication. We previously demonstrated the …

MicroRNA-146b negatively affects bovine embryo development and quality

KC Pavani, G XueFeng, J Chunduru, T Meese… - …, 2024 - rep.bioscientifica.com
In brief MicroRNAs (miRNAs) carried in extracellular vesicles are one of the essential factors
for embryo development. This study demonstrates that miRNA-146 b has negative impacts …

[HTML][HTML] tRNAGlu-derived fragments from embryonic extracellular vesicles modulate bovine embryo hatching

Y Fan, KC Pavani, K Smits, A Van Soom… - Journal of Animal …, 2024 - Springer
Transfer RNA-derived small RNAs (tsRNAs) have been shown to be involved in early
embryo development and repression of endogenous retroelements in embryos and stem …

Selection and application of small non-coding RNAs for normalizing RT-qPCR data of bovine preimplantation embryo conditioned medium

Y Fan, KC Pavani, OB Pascottini, K Smits, A Van Soom… - Theriogenology, 2024 - Elsevier
Small non-coding RNAs (sncRNAs) present in the conditioned medium (CM) of bovine
preimplantation embryos are potential noninvasive biomarkers for assessing embryo quality …