Can melatonin reduce the severity of COVID-19 pandemic?

A Shneider, A Kudriavtsev… - International reviews of …, 2020 - Taylor & Francis
The current COVID-19 pandemic is one of the most devastating events in recent history. The
virus causes relatively minor damage to young, healthy populations, imposing life …

Mitochondrial dysfunction and endoplasmic reticulum stress in the promotion of fibrosis in obstructive nephropathy induced by unilateral ureteral obstruction

E Martínez‐Klimova, OE Aparicio‐Trejo… - …, 2020 - Wiley Online Library
Obstructive nephropathy favors the progression to chronic kidney disease (CKD), a severe
health problem worldwide. The unilateral ureteral obstruction (UUO) model is used to study …

Renalase attenuates mitochondrial fission in cisplatin-induced acute kidney injury via modulating sirtuin-3

Z Huang, Q Li, Y Yuan, C Zhang, L Wu, XI Liu, W Cao… - Life sciences, 2019 - Elsevier
Aims Acute kidney injury (AKI) can limit the clinical use of cisplatin in cancer treatment. The
drivers of cisplatin-induced AKI include oxidative stress, mitochondrial dysfunction and …

[HTML][HTML] The effect of eight weeks resistance and endurance training on some angiogenesis factors of hippocampus tissue in male wistar rats

M Sadegh Ghomi, M Kashef… - Journal of Sport and …, 2021 - joeppa.sbu.ac.ir
Purpose: One of the cause of adaptations due to exercise training is increased capillary
density or angiogenesis. increased blood flow to hippocampus tissue causes improvement …

[HTML][HTML] مقایسة اثر تمرین تناوبی شدید و مقاومتی فزاینده بر بیان ژن ATF3 عضلة قلبی موش‌های صحرایی دیابتی نر

سفال منش, شهاب الدین, خالدی, ندا, رجبی… - نشریه فیزیولوژی ورزش و …, 2021‎ - joeppa.sbu.ac.ir
هدف: از سازوکارهای مؤثر در انجام بهتر عملکرد عضلانی در ورزشکاران، القای ظرفیت
پیش‌فعال‌سازی (PAP) در روش گرم کردن است. ازاین‌رو، پژوهش حاضر به‌منظور بررسی تأثیر گرم …

[HTML][HTML] The multi-faceted nature of renalase for mitochondrial dysfunction improvement in cardiac disease

D Stojanovic, M Stojanovic, J Milenkovic, A Velickov… - Cells, 2023 - mdpi.com
The cellular mechanisms and signaling network that guide the cardiac disease
pathophysiology are inextricably intertwined, which explains the current scarcity of effective …

[HTML][HTML] Extracellular vesicles in redox signaling and metabolic regulation in chronic kidney disease

OE Aparicio-Trejo, AK Aranda-Rivera, H Osorio-Alonso… - Antioxidants, 2022 - mdpi.com
Chronic kidney disease (CKD) is a world health problem increasing dramatically. The onset
of CKD is driven by several mechanisms; among them, metabolic reprogramming and …

Temporal characterization of mitochondrial impairment in the unilateral ureteral obstruction model in rats

AP Jiménez-Uribe, B Bellido, OE Aparicio-Trejo… - Free Radical Biology …, 2021 - Elsevier
Renal fibrosis is a well-known mechanism that favors chronic kidney disease (CKD)
development in obstructive nephropathy, a significant pathology worldwide. Fibrosis …

Oxidative storm induced by tryptophan metabolites: missing link between atherosclerosis and chronic kidney disease

I Kwiatkowska, JM Hermanowicz… - Oxidative Medicine …, 2020 - Wiley Online Library
Chronic kidney disease (CKD) occurrence is rising all over the world. Its presence is
associated with an increased risk of premature death from cardiovascular disease (CVD) …

Renalase is localized to the small intestine crypt and expressed upon the activation of NF-κB p65 in mice model of fasting-induced oxidative stress

K Aoki, K Yanazawa, K Tokinoya, T Sugasawa… - Life sciences, 2021 - Elsevier
Aims Renalase expression is regulated by Nuclear Factor (NF)-κB and hypoxia inducible
factor (HIF)-1α, and antioxidative stress function in renal cells were reported. However …