The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular
component), and cellular components include cancer cells and non-malignant cells such as …

Hypoxia is an integral component of the tumor microenvironment. Either as chronic or
cycling hypoxia, it exerts a similar effect on cancer processes by activating hypoxia-inducible …

Mesenchymal stem cells (MSCs) are promising alternative agents for the treatment of
inflammatory disorders due to their immunomodulatory functions, and several clinical trials …

Cells have emerged as a promising new form of drug delivery carriers owing to their
distinguished advantages such as naturally bypassing immune recognition, intrinsic …

Stem cell homing is a multistep endogenous physiologic process that is also used by
exogenously administered hematopoietic stem and progenitor cells (HSPCs). This multistep …

Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …

Abstract Background Mesenchymal stem cells (MSCs) therapy is a novel treatment strategy
for cancer and a wide range of diseases with an excessive immune response such as …

Chemokine receptors are members of the G protein-coupled receptor superfamily. These
receptors are intimately involved in cell movement, and thus play a critical role in several …

Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …

Mesenchymal stem/stromal cells (MSCs) have been widely studied in the field of
regenerative medicine for applications in the treatment of several disease settings. The …