Studies in neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease
and Amyotrophic lateral sclerosis, Huntington's disease, and so on, have suggested that …

Cellular senescence is a homeostatic biological process characterized by a permanent state
of cell cycle arrest that can contribute to the decline of the regenerative potential and …

The proliferation and activation of microglial cells is a hallmark of several neurodegenerative
conditions. This mechanism is regulated by the activation of the colony-stimulating factor 1 …

Neuroinflammation and microglial activation are significant processes in Alzheimer's
disease pathology. Recent genome-wide association studies have highlighted multiple …

Alzheimer′ s disease (AD) is the most common neurodegenerative disorder to date.
Neuropathological hallmarks are β‐amyloid (Aβ) plaques and neurofibrillary tangles, but the …

The study of the dynamics and functions of microglia in the healthy and diseased brain is a
matter of intense scientific activity. The application of new techniques and new experimental …

Neuroinflammation constitutes a fundamental process involved in the progression of several
neurodegenerative disorders, such as Parkinson's disease, Alzheimer's disease …

Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease
(AD) brain, and it does so with the full complexity of local peripheral inflammatory responses …

In 1907, Alois Alzheimer described the case of a 51 year old woman who presented with a
relatively rapidly deteriorating memory along with psychiatric disturbances. She died four …

Alzheimer's disease (AD) is the leading cause of dementia worldwide. Most AD patients
develop the disease in late life, named late onset AD (LOAD). Currently, the most …