[HTML][HTML] A comparison of logistic regression, logic regression, classification tree, and random forests to identify effective gene-gene and gene-environmental …

W Yoo, BA Ference, ML Cote… - International journal of …, 2012 - ncbi.nlm.nih.gov
Genome wide association studies (GWAS) have identified numerous single nucleotide
polymorphisms (SNPs) that are associated with a variety of common human diseases. Due …

[HTML][HTML] E2-2 dependent plasmacytoid dendritic cells control autoimmune diabetes

L Hansen, A Schmidt-Christensen, S Gupta… - PloS one, 2015 - journals.plos.org
Autoimmune diabetes is a consequence of immune-cell infiltration and destruction of
pancreatic β-cells in the islets of Langerhans. We analyzed the cellular composition of the …

[HTML][HTML] Transcriptional regulatory networks of circulating immune cells in type 1 diabetes: A community knowledgebase

SA Ochsner, RT Pillich, D Rawool, JS Grethe… - Iscience, 2022 - cell.com
Investigator-generated transcriptomic datasets interrogating circulating immune cell (CIC)
gene expression in clinical type 1 diabetes (T1D) have underappreciated re-use value …

Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation

G Monteleone, P Buchwald, L Inverardi… - US Patent …, 2018 - Google Patents
WO-2005/050202 A2 J-2005/030202 A2 WO-2006-035434 A2 WO-2007/039151 Al WO-
2009/129544 Al WO-2010/054826 A1 WO-2013/037970 A1 WO-2014/140333 A1 WO …

Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation

G Monteleone, P Buchwald, L Inverardi… - US Patent …, 2019 - Google Patents
Disclosed herein are methods for treating/and or preventing diabetes using a specific
inhibitor of SMAD7 expression or function. Also disclosed are methods of promoting organ …

Exploiting linkage disequilibrium for ultrahigh-dimensional genome-wide data with an integrated statistical approach

M Carlsen, G Fu, S Bushman, C Corcoran - Genetics, 2016 - academic.oup.com
Genome-wide data with millions of single-nucleotide polymorphisms (SNPs) can be highly
correlated due to linkage disequilibrium (LD). The ultrahigh dimensionality of big data brings …

An Integrated Approach to Exploit Linkage Disequilibrium for Ultra High Dimensional Genome-wide Data

M Carlsen - 2015 - digitalcommons.usu.edu
This paper presents improved methods for analysis of genome-wide association studies in
contemporary genetic research. Thanks to current sequencing methods, half to one million …

Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation

G Monteleone, P Buchwald, L Inverardi, A Pileggi… - 2013 - Google Patents
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C (= O) C (NC (= O)
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …

Identifying molecular factors influencing B cells in Type 1 Diabetes

J Stolp - 2011 - unsworks.unsw.edu.au
Type 1 Diabetes is an autoimmune disease where the immune system destroys the insulin
producing β cells within the pancreas. The incidence of this disease has risen steadily in …