Theoretical and experimental studies have shown that restitution of the cardiac action
potential (AP) duration (APD) plays a major role in predisposing ventricular tachycardia to …

We propose an isogeometric collocation approach to an efficient solution of the
monodomain reaction–diffusion equation. The strong formulation, compared to standard …

Finite element (FE) cardiac electro‐physiology solvers commonly have ionic current
determined at mesh nodes but required element interiors. We consider two interpolation …

Intracellular calcium (Ca) cycling dynamics in cardiac myocytes is regulated by a complex
network of spatially distributed organelles, such as sarcoplasmic reticulum (SR) …

Engineered heart tissues (EHTs) built from human induced pluripotent stem cell-derived
cardiomyocytes (hiPSC-CMs) showed promising results for cardiac function restoration …

The tendency of atrial or ventricular fibrillation to terminate spontaneously in finite-sized
tissue is known as the critical mass hypothesis. Previous studies have shown that dynamical …

This paper deals with mathematical models of cardiac bioelectric activity at both the cell and
tissue levels, their integration in coupled models and their numerical simulation. The …

We have constructed computational models of canine ventricular cells and tissues,
ultimately combining detailed tissue architecture and heterogeneous transmural …

In this technical note we show the promise of using graphic processing units (GPUs) to
accelerate simulations of electrical wave propagation in cardiac tissue, one of the more …

Spatially discordant alternans (SDA) of action potential duration (APD) is a phenomenon
where different regions of cardiac tissue exhibit an alternating sequence of APD that are out …