STAT5 in cancer and immunity

A Rani, JJ Murphy - Journal of Interferon & Cytokine Research, 2016 - liebertpub.com
Signal transducers and activators of transcription 5 (STAT5a and STAT5b) are highly
homologous proteins that are encoded by 2 separate genes and are activated by Janus …

Cancer incidence in patients with schizophrenia and their first‐degree relatives–a meta‐analysis

VS Catts, SV Catts, BI O'toole… - Acta Psychiatrica …, 2008 - Wiley Online Library
Objective: Controversy concerning cancer incidence in schizophrenia exists because of
heterogeneous study findings. Method: A meta‐analysis was performed on standardized …

The Mediterranean diet, plasma metabolome, and cardiovascular disease risk

J Li, M Guasch-Ferré, W Chung… - European heart …, 2020 - academic.oup.com
Aims To investigate whether metabolic signature composed of multiple plasma metabolites
can be used to characterize adherence and metabolic response to the Mediterranean diet …

[HTML][HTML] Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism

M Germain, DI Chasman, H De Haan, W Tang… - The American Journal of …, 2015 - cell.com
Venous thromboembolism (VTE), the third leading cause of cardiovascular mortality, is a
complex thrombotic disorder with environmental and genetic determinants. Although several …

Cross-ancestry investigation of venous thromboembolism genomic predictors

F Thibord, D Klarin, JA Brody, MH Chen, MG Levin… - Circulation, 2022 - Am Heart Assoc
Background: Venous thromboembolism (VTE) is a life-threatening vascular event with
environmental and genetic determinants. Recent VTE genome-wide association studies …

Novel common genetic susceptibility loci for colorectal cancer

SL Schmit, CK Edlund, FR Schumacher… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Previous genome-wide association studies (GWAS) have identified 42 loci (P<
5× 10− 8) associated with risk of colorectal cancer (CRC). Expanded consortium efforts …

Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women

AH Eliassen, SA Missmer, SS Tworoger… - Journal of the …, 2006 - academic.oup.com
Background: Higher levels of endogenous sex steroid hormones are associated with
increased risks of breast cancer in postmenopausal women. Data for premenopausal …

[HTML][HTML] Mammographic density and risk of breast cancer by age and tumor characteristics

KA Bertrand, RM Tamimi, CG Scott, MR Jensen… - Breast Cancer …, 2013 - Springer
Introduction Understanding whether mammographic density (MD) is associated with all
breast tumor subtypes and whether the strength of association varies by age is important for …

A 20-year prospective study of plasma prolactin as a risk marker of breast cancer development

SS Tworoger, AH Eliassen, X Zhang, J Qian, PM Sluss… - Cancer research, 2013 - AACR
Understanding how the timing of exposure to endogenous hormones influences cancer
development is critical to elucidating disease etiology. Prolactin increases proliferation and …

Gene–environment interaction between HLA-DRB1 shared epitope and heavy cigarette smoking in predicting incident rheumatoid arthritis

EW Karlson, SC Chang, J Cui, LB Chibnik… - Annals of the …, 2010 - ard.bmj.com
Background: Previous studies have reported an interaction between ever cigarette smoking
and the presence of the human leukocyte antigen (HLA)-DRB1 shared epitope (SE) …