A review on the reciprocal interactions between neuroinflammatory processes and substance use and misuse, with a focus on alcohol misuse
Background: The last decade has witnessed a surge of findings implicating
neuroinflammatory processes as pivotal players in substance use disorders. The …
neuroinflammatory processes as pivotal players in substance use disorders. The …
[HTML][HTML] The neuroimmune system and the cerebellum
DL Gruol - The Cerebellum, 2023 - Springer
The recognition that there is an innate immune system of the brain, referred to as the
neuroimmune system, that preforms many functions comparable to that of the peripheral …
neuroimmune system, that preforms many functions comparable to that of the peripheral …
[HTML][HTML] Ethanol induces neuroinflammation in a chronic plus binge mouse model of alcohol use disorder via TLR4 and MyD88-dependent signaling
KN Holloway, JC Douglas, TM Rafferty, CJM Kane… - Cells, 2023 - mdpi.com
Ethanol induces neuroinflammation, which is believed to contribute to the pathogenesis of
alcohol use disorder (AUD). Toll-like receptors (TLRs) are a group of pattern recognition …
alcohol use disorder (AUD). Toll-like receptors (TLRs) are a group of pattern recognition …
Binge ethanol exposure in advanced age elevates neuroinflammation and early indicators of neurodegeneration and cognitive impairment in female mice
PE Anton, LN Rutt, ML Kaufman, N Busquet… - Brain, Behavior, and …, 2024 - Elsevier
Binge drinking is rising among aged adults (> 65 years of age), however the contribution of
alcohol misuse to neurodegenerative disease development is not well understood. Both …
alcohol misuse to neurodegenerative disease development is not well understood. Both …
[HTML][HTML] Cerebellar transcriptomic analysis in a chronic plus binge mouse model of alcohol use disorder demonstrates ethanol-induced neuroinflammation and altered …
KN Holloway, MR Pinson, JC Douglas, TM Rafferty… - Cells, 2023 - mdpi.com
Alcohol use disorder (AUD) is one of the most common preventable mental health disorders
and can result in pathology within the CNS, including the cerebellum. Cerebellar alcohol …
and can result in pathology within the CNS, including the cerebellum. Cerebellar alcohol …
[HTML][HTML] Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation
Background Neuroinflammation is a widely studied phenomenon underlying various
neurodegenerative diseases. Earlier study demonstrated that pharmacological activation of …
neurodegenerative diseases. Earlier study demonstrated that pharmacological activation of …
[HTML][HTML] Two-Month Voluntary Ethanol Consumption Promotes Mild Neuroinflammation in the Cerebellum but Not in the Prefrontal Cortex, Hippocampus, or Striatum of …
P Berríos-Cárcamo, S Núñez, J Castañeda… - International Journal of …, 2024 - mdpi.com
Chronic ethanol exposure often triggers neuroinflammation in the brain's reward system,
potentially promoting the drive for ethanol consumption. A main marker of …
potentially promoting the drive for ethanol consumption. A main marker of …
Binge Ethanol and the Aging Brain: Exploring Mechanisms of Neuroinflammation and Neurodegeneration
PE Anton - 2024 - search.proquest.com
The number of aged adults (> 65 years) that suffer from neurodegenerative diseases
including Alzheimer's disease (AD) and related dementias (ADRD) is rising. Although the …
including Alzheimer's disease (AD) and related dementias (ADRD) is rising. Although the …
[图书][B] Ethanol Effects on the Brain in Animal Models of Fetal Alcohol Spectrum Disorders and Alcohol Use Disorder
KN Holloway - 2022 - search.proquest.com
Alcohol abuse can lead to fetal alcohol spectrum disorders (FASD) and alcohol use disorder
(AUD) which are characterized by impaired function of the central nervous system (CNS) …
(AUD) which are characterized by impaired function of the central nervous system (CNS) …