Puberty is a time of considerable metabolic and hormonal change. Notably, puberty is
associated with a marked decrease in insulin sensitivity, on par with that seen during …

Growth hormone (GH) is important for promotion of somatic growth and the regulation of
substrate metabolism. Metabolic action of GH occurs in multiple tissues including the liver …

The mechanisms for controlling food intake involve mainly an interplay between gut, brain,
and adipose tissue (AT), among the major organs. Parasympathetic, sympathetic, and other …

The circadian clock provides cue-independent anticipatory signals for diurnal rhythms of
baseline glucose levels and glucose tolerance. The central circadian clock is located in the …

Obesity is associated with infertility in women through multiple and complex mechanisms.
Briefly, the adipose tissue through the production of many factors, such as leptin, free fatty …

Obesity has become one of the most common medical problems in developed countries,
and this disorder is associated with high incidences of hypertension, dyslipidaemia …

Growth Hormone Assessment in Adults Growth hormone synthesis and physiology are
discussed in the context of recombinant growth hormone use in adults. Growth hormone …

New appetite‐regulating antiobesity treatments such as semaglutide and agents under
investigation such as tirzepatide show promise in achieving weight loss of 15% or more …

Both maternal and offspring-derived factors contribute to lifelong growth and bone mass
accrual, although the specific role of maternal deficiencies in the growth and bone mass of …

Background Many genetically multi‐modified donor lines for xenotransplantation have a
background of domestic pigs with rapid body and organ growth. The intrinsic growth …