Vitamin B12–dependent taurine synthesis regulates growth and bone mass

P Roman-Garcia, I Quiros-Gonzalez… - The Journal of …, 2014 - Am Soc Clin Investig
Both maternal and offspring-derived factors contribute to lifelong growth and bone mass
accrual, although the specific role of maternal deficiencies in the growth and bone mass of …

Effect of growth hormone on insulin signaling

R Sharma, JJ Kopchick, V Puri, VM Sharma - Molecular and cellular …, 2020 - Elsevier
Growth hormone (GH) is a pleiotropic hormone that coordinates an array of physiological
processes, including effects on bone, muscle, and fat, ultimately resulting in growth …

[PDF][PDF] Growth hormone deficiency and NAFLD: An overlooked and underrecognized link

I Doycheva, D Erickson, KD Watt - Hepatology Communications, 2022 - Wiley Online Library
Growth hormone and its mediator insulin‐like growth factor‐1 exert their effect on different
organs and control various physiologic metabolic processes. Adult growth hormone …

Genes and longevity of lifespan

MN Bin-Jumah, MS Nadeem, SJ Gilani… - International Journal of …, 2022 - mdpi.com
Aging is a complex process indicated by low energy levels, declined physiological activity,
stress induced loss of homeostasis leading to the risk of diseases and mortality. Recent …

Minireview: mechanisms of growth hormone-mediated gene regulation

DJ Chia - Molecular Endocrinology, 2014 - academic.oup.com
GH exerts a diverse array of physiological actions that include prominent roles in growth and
metabolism, with a major contribution via stimulating IGF-1 synthesis. GH achieves its effects …

[HTML][HTML] β Cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood

AL Castell, C Goubault, M Ethier, G Fergusson… - JCI insight, 2022 - ncbi.nlm.nih.gov
Puberty is associated with transient insulin resistance that normally recedes at the end of
puberty; however, in overweight children, insulin resistance persists, leading to an increased …

Long-term safety of growth hormone in adults with growth hormone deficiency: overview of 15 809 GH-treated patients

G Johannsson, P Touraine… - The Journal of …, 2022 - academic.oup.com
Context Data on long-term safety of growth hormone (GH) replacement in adults with GH
deficiency (GHD) are needed. Objective We aimed to evaluate the safety of GH in the full …

Effects of adult growth hormone deficiency and replacement therapy on the cardiometabolic risk profile

B Ratku, V Sebestyén, A Erdei, EV Nagy, Z Szabó… - Pituitary, 2022 - Springer
Adult growth hormone deficiency (AGHD) is considered a rare endocrine disorder involving
patients with childhood-onset and adult-onset growth hormone deficiency (AoGHD) and …

Covid-19 and growth hormone/insulin-like growth factor 1: study in critically and non-critically ill patients

I Ilias, A Diamantopoulos, E Botoula… - Frontiers in …, 2021 - frontiersin.org
Objective We aimed to measure insulin-like growth factor 1 (IGF1) and growth hormone (GH)
in critically and non-critically ill patients with Covid-19 and assess them vis-a-vis clinical and …

The complex relationship between obesity and the somatropic axis: the long and winding road

S Savastano, C Di Somma, L Barrea, A Colao - Growth Hormone & IGF …, 2014 - Elsevier
Despite the considerable body of evidence pointing to a possible relationship between the
state of the adipose tissue depots and regulation of the somatotropic axis, to date the …