MicroRNA‐binding site polymorphisms and risk of colorectal cancer: A systematic review and meta‐analysis

M Gholami, B Larijani, F Sharifi… - Cancer …, 2019 - Wiley Online Library
Genetic variations in miRNAs binding site might participate in cancer risk. This study aimed
to systematically review the association between miRNA‐binding site polymorphisms and …

Chasing the personalized medicine dream through biomarker validation in colorectal cancer

H Patil, SG Saxena, CJ Barrow, JR Kanwar, A Kapat… - Drug Discovery …, 2017 - Elsevier
Highlights•mCRC patients' survival outcomes pose major treatment challenge for
oncologists.•Personalized medicine is an evolving approach for cancer management …

The association of the placental MTHFR 3′‐UTR polymorphisms, promoter methylation, and MTHFR expression with preeclampsia

A Mohammadpour‐Gharehbagh… - Journal of Cellular …, 2018 - Wiley Online Library
Preeclampsia (PE) is a pregnancy specific complication arises in presence of the placenta
and disappears immediately after delivery. Therefore, the aim of the present study was to …

Interplay between 3′-UTR polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and the risk of ischemic stroke

JO Kim, HS Park, CS Ryu, JW Shin, J Kim, SH Oh… - Scientific reports, 2017 - nature.com
Stroke incidence is a multifactorial disease and especially hyperhomocysteinemia is
associated with a higher risk of stroke. Previous studies have reported a folate metabolism …

Methylenetetrahydrofolate reductase polymorphisms and colorectal cancer prognosis: A meta‐analysis

XL Chen, YM Wang, F Zhao, Z Chen… - The Journal of Gene …, 2019 - Wiley Online Library
Background The present study focused on understanding the prognostic value of the
methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms rs1801133 …

3′-UTR polymorphisms in thymidylate synthase with colorectal cancer prevalence and prognosis

YJ Jeon, SH Cho, EJ Kim, CS Ryu, HS Park… - Journal of Personalized …, 2021 - mdpi.com
Colorectal cancer (CRC) is the third most common type of cancer and the second leading
cause of cancer-related mortality in Western countries. Polymorphisms in one-carbon …

The Roles of MTRR and MTHFR Gene Polymorphisms in Colorectal Cancer Survival

Y Wang, M Du, J Vallis, M Shariati, PS Parfrey… - Nutrients, 2022 - mdpi.com
Background: Paradoxically epidemiological data illustrate a negative relationship between
dietary folate intake and colorectal cancer (CRC) risk. The occurrence and progression of …

3′-UTR Polymorphisms of MTHFR and TS Associated with Osteoporotic Vertebral Compression Fracture Susceptibility in Postmenopausal Women

TK Ahn, JO Kim, HW Kim, HS Park, JH Shim… - International journal of …, 2018 - mdpi.com
Postmenopausal osteoporosis is one of the most prominent diseases in postmenopausal
women and it is increasing in prevalence with the aging population. Furthermore …

Genetic variants in 3′‐UTRs of MTHFR in the pregnancies complicated with preeclampsia and bioinformatics analysis

A Mohammadpour‐Gharehbagh… - Journal of cellular …, 2018 - Wiley Online Library
Preeclampsia (PE) as a pregnancy‐specific disorder is the major cause of mortality and
morbidity of mothers and fetuses. This study attempts to investigate the possible association …

[HTML][HTML] A variant in SIRT2 gene 3′-UTR is associated with susceptibility to colorectal cancer

Y Yang, J Ding, ZG Gao, ZJ Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
SIRT2 is a member of sirtuin family and is associated with cell growth in various cancers. In
this study, we searched for variants in functional region of SIRT2 gene and identify rs2015 …