Periodontal diseases, such as chronic periodontitis, share common inflammatory risk factors
with other systemic and chronic inflammatory disorders. Mucosal tissues, such as oral …

Abstract Interleukin (IL)-1β, a pro-inflammatory cytokine, was elevated and participates in
periodontitis. Not only the link between IL-1β and periodontitis was proved by clinical …

The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …

Alveolar bone is a unique osseous tissue due to the proximity of dental plaque biofilms.
Periodontal health and homeostasis are mediated by a balanced host immune response to …

Periodontal diseases (PD) are chronic infectious inflammatory diseases characterized by the
destruction of tooth-supporting structures, being the presence of periodontopathogens …

Preshaw PM, Taylor JJ. How has research into cytokine interactions and their role in driving
immune responses impacted our understanding of periodontitis? J Clin Periodontol 2011; …

Aims To compare gingival crevicular fluid (GCF) cytokines/chemokines levels between
periodontally healthy subjects and subjects diagnosed with chronic periodontitis (C h P) …

Abstract Background and Objectives The receptor activator of NF‐κB ligand‐osteoprotegerin
(RANKL‐OPG) bi‐molecular system is the “bottle‐neck” regulator of osteoclastogenesis and …

Monocytes and macrophages are major cellular components of the innate immunity that play
essential roles in tissue homeostasis. The contribution of different subsets of monocytes …

Porphyromonas gingivalis is a leading pathogen in chronic periodontitis, a disease process
involving progressive destruction of the tissues that support the teeth. Recently, the …