The human gut microbiota: a key mediator of osteoporosis and osteogenesis
KD Seely, CA Kotelko, H Douglas, B Bealer… - International journal of …, 2021 - mdpi.com
An expanding body of research asserts that the gut microbiota has a role in bone
metabolism and the pathogenesis of osteoporosis. This review considers the human gut …
metabolism and the pathogenesis of osteoporosis. This review considers the human gut …
[HTML][HTML] Potential bioactive coating system for high-performance absorbable magnesium bone implants
Magnesium alloys are considered the most suitable absorbable metals for bone fracture
fixation implants. The main challenge in absorbable magnesium alloys is their high …
fixation implants. The main challenge in absorbable magnesium alloys is their high …
Dual actions of osteoclastic-inhibition and osteogenic-stimulation through strontium-releasing bioactive nanoscale cement imply biomaterial-enabled osteoporosis …
Repair of defective hard-tissues in osteoporotic patients faces significantly challenges with
limited therapeutic options. Although biomedical cements are considered promising …
limited therapeutic options. Although biomedical cements are considered promising …
Advances in multifunctional bioactive coatings for metallic bone implants
MP Nikolova, MD Apostolova - Materials, 2022 - mdpi.com
To fix the bone in orthopedics, it is almost always necessary to use implants. Metals provide
the needed physical and mechanical properties for load-bearing applications. Although …
the needed physical and mechanical properties for load-bearing applications. Although …
Effects of bisphosphonates on osteoporosis: Focus on zoledronate
Osteoporosis is a bone disease that mainly affects older people and postmenopausal
women. Lack of proper treatment for this disease gives rise to many problems in patients …
women. Lack of proper treatment for this disease gives rise to many problems in patients …
[HTML][HTML] An osteopenic/osteoporotic phenotype delays alveolar bone repair
Aging is associated with a function decline in tissue homeostasis and tissue repair. Aging is
also associated with an increased incidence in osteopenia and osteoporosis, but whether …
also associated with an increased incidence in osteopenia and osteoporosis, but whether …
Medication-related osteonecrosis of the jaw (MRONJ): a review of pathogenesis hypothesis and therapy strategies
A Jiang, Z Zhang, X Qiu, Q Guo - Archives of Toxicology, 2024 - Springer
Medication-related osteonecrosis of the jaw (MRONJ), a severe side effect caused by
antiresorptive antiangiogenic medication, particularly bisphosphonates (BPs), has become a …
antiresorptive antiangiogenic medication, particularly bisphosphonates (BPs), has become a …
The biology of fracture healing in osteoporosis and in the presence of anti-osteoporotic drugs
DJ Hak - Injury, 2018 - Elsevier
Compromised bone strength in osteoporosis predisposes patients to an increased fracture
risk. The management of these fractures is complicated due to the poor bone quality, which …
risk. The management of these fractures is complicated due to the poor bone quality, which …
Systems analysis of avascular necrosis of femoral head using integrative data analysis and literature mining delineates pathways associated with disease
AA Naik, A Narayanan, P Khanchandani… - Scientific Reports, 2020 - nature.com
Avascular necrosis of femoral head (AVNFH) is a debilitating disease, which affects the
middle aged population. Though the disease is managed using bisphosphonate, it …
middle aged population. Though the disease is managed using bisphosphonate, it …
Pharmacological agents for bone fracture healing: talking points from recent clinical trials
F Migliorini, F Cocconi, G Vecchio… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Pharmacological strategies might influence bone healing in terms of time to
union or quality of mature bone. This expert opinion discussed the current level I evidence …
union or quality of mature bone. This expert opinion discussed the current level I evidence …