[HTML][HTML] Recent levels and trends in HIV incidence rates among adolescent girls and young women in ten high-prevalence African countries: a systematic review and …

I Birdthistle, C Tanton, A Tomita, K de Graaf… - The Lancet Global …, 2019 - thelancet.com
Background The roll-out of antiretroviral therapy (ART) has changed contexts of HIV risk, but
the influence on HIV incidence among young women is not clear. We aimed to summarise …

[HTML][HTML] The disconnect between individual-level and population-level HIV prevention benefits of antiretroviral treatment

S Baral, A Rao, P Sullivan, N Phaswana-Mafuya… - The lancet HIV, 2019 - thelancet.com
In 2019, the HIV pandemic is growing and soon over 40 million people will be living with
HIV. Effective population-based approaches to decrease HIV incidence are as relevant as …

[HTML][HTML] Effect of universal testing and treatment on HIV incidence—HPTN 071 (PopART)

RJ Hayes, D Donnell, S Floyd, N Mandla… - … England Journal of …, 2019 - Mass Medical Soc
Background A universal testing and treatment strategy is a potential approach to reduce the
incidence of human immunodeficiency virus (HIV) infection, yet previous trial results are …

[HTML][HTML] Universal testing, expanded treatment, and incidence of HIV infection in Botswana

J Makhema, KE Wirth, M Pretorius Holme… - … England Journal of …, 2019 - Mass Medical Soc
Background The feasibility of reducing the population-level incidence of human
immunodeficiency virus (HIV) infection by increasing community coverage of antiretroviral …

Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults with HIV in …

ND Labhardt, I Ringera, TI Lejone, T Klimkait… - Jama, 2018 - jamanetwork.com
Importance Home-based HIV testing is a frequently used strategy to increase awareness of
HIV status in sub-Saharan Africa. However, with referral to health facilities, less than half of …

[HTML][HTML] Community-based antiretroviral therapy versus standard clinic-based services for HIV in South Africa and Uganda (DO ART): a randomised trial

RV Barnabas, AA Szpiro, H van Rooyen… - The lancet Global …, 2020 - thelancet.com
Background Community-based delivery of antiretroviral therapy (ART) for HIV, including
ART initiation, clinical and laboratory monitoring, and refills, could reduce barriers to …

What do the Universal Test and Treat trials tell us about the path to HIV epidemic control?

D Havlir, S Lockman, H Ayles… - Journal of the …, 2020 - Wiley Online Library
Introduction Achieving HIV epidemic control globally will require new strategies to
accelerate reductions in HIV incidence and mortality. Universal test and treat (UTT) was …

Cohort profile update: Africa Centre Demographic Information System (ACDIS) and population-based HIV survey

D Gareta, K Baisley, T Mngomezulu… - International journal …, 2021 - academic.oup.com
ACDIS has made important contributions to our understanding of the HIV epidemic.
However, despite significant increases in antiretroviral therapy (ART) coverage, HIV …

[HTML][HTML] Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase

MJ Siedner, MA Moorhouse, B Simmons… - Nature …, 2020 - nature.com
Little is known about the impact of pretreatment drug resistance (PDR) on the efficacy of
second generation integrase inhibitors. We sequenced pretreatment plasma specimens …

Large age shifts in HIV-1 incidence patterns in KwaZulu-Natal, South Africa

A Akullian, A Vandormael, JC Miller… - Proceedings of the …, 2021 - National Acad Sciences
Recent declines in adult HIV-1 incidence have followed the large-scale expansion of
antiretroviral therapy and primary HIV prevention across high-burden communities of sub …