Organ-specific endothelial cell differentiation and impact of microenvironmental cues on endothelial heterogeneity

L Gifre-Renom, M Daems, A Luttun… - International journal of …, 2022 - mdpi.com
Endothelial cells throughout the body are heterogeneous, and this is tightly linked to the
specific functions of organs and tissues. Heterogeneity is already determined from …

Development of a magnetic microrobot for carrying and delivering targeted cells

J Li, X Li, T Luo, R Wang, C Liu, S Chen, D Li, J Yue… - Science robotics, 2018 - science.org
The precise delivery of targeted cells through magnetic field–driven microrobots/carriers is a
promising technique for targeted therapy and tissue regeneration. This paper presents a …

Multifunctional microrobot with real-time visualization and magnetic resonance imaging for chemoembolization therapy of liver cancer

G Go, A Yoo, KT Nguyen, M Nan, BA Darmawan… - Science …, 2022 - science.org
Microrobots that can be precisely guided to target lesions have been studied for in vivo
medical applications. However, existing microrobots have challenges in vivo such as …

[HTML][HTML] Fibrosis and hepatic regeneration mechanism

E Zuñiga-Aguilar… - Translational …, 2022 - ncbi.nlm.nih.gov
Liver cirrhosis is the final stage of continuous hepatic inflammatory activity derived by viral,
metabolic or autoimmune origin. In the last years, cirrhosis was considered a unique and …

Super-resolution ultrasound localization microscopy based on a high frame-rate clinical ultrasound scanner: An in-human feasibility study

C Huang, W Zhang, P Gong, UW Lok… - Physics in Medicine …, 2021 - iopscience.iop.org
Non-invasive detection of microvascular alterations in deep tissues in vivo provides critical
information for clinical diagnosis and evaluation of a broad-spectrum of pathologies …

The liver, a functionalized vascular structure

S Lorente, M Hautefeuille, A Sanchez-Cedillo - Scientific Reports, 2020 - nature.com
The liver is not only the largest organ in the body but also the one playing one of the most
important role in the human metabolism as it is in charge of transforming toxic substances in …

A Soft Biodegradable Chitosan‐Based Medical Microrobot with Optimized Structural Design and X‐Ray Visibility for Targeted Vessel Chemoembolization

G Go, HW Song, M Nan, J Lee, S Kim… - Advanced Functional …, 2023 - Wiley Online Library
Although many medical microrobots have been developed for treating diseases, their
designs have not been optimized for disease environments and their functionality and …

HEDOS—a computational tool to assess radiation dose to circulating blood cells during external beam radiotherapy based on whole-body blood flow simulations

J Shin, S Xing, L McCullum, A Hammi… - Physics in Medicine …, 2021 - iopscience.iop.org
We have developed a time-dependent computational framework, hematological dose
(HEDOS), to estimate dose to circulating blood cells from radiation therapy treatment fields …

[HTML][HTML] Hierarchical modeling of the liver vascular system

AM Torres Rojas, S Lorente, M Hautefeuille… - Frontiers in …, 2021 - frontiersin.org
The liver plays a key role in the metabolic homeostasis of the whole organism. To carry out
its functions, it is endowed with a peculiar circulatory system, made of three main dendritic …

Fiber optic sensors-based thermal analysis of perfusion-mediated tissue cooling in liver undergoing laser ablation

E De Vita, M De Landro, C Massaroni… - IEEE Transactions …, 2020 - ieeexplore.ieee.org
The current challenge in the field of thermo-ablative treatments of tumors is to achieve a
balance between complete destruction of malignant cells and safeguarding of the …