Mitochondria play many critical roles in cells, not only by supplying energy, but also by
supplying metabolites, buffering Ca2+ levels and regulating apoptosis. During oocyte …

Background Evolutionary theory indicates that the dynamics of aging in the soma and
reproductive tissues may be distinct. This difference arises from the fact that only the …

Mitochondria have a crucial role in cellular function and exhibit remarkable plasticity,
adjusting both their structure and activity to meet the changing energy demands of a cell …

Anticancer drugs, such as alkylating agents, can affect male fertility by targeting the DNA of
proliferative spermatogonial stem cells (SSC). Therefore, to reduce such side effects, other …

A majority of ovarian follicles are lost to natural death, but the disruption of factors involved in
maintenance of the oocyte pool results in a further untimely follicular depletion known as …

In vitro maturation (IVM) is an alternative assisted reproductive technology with reduced
hormone-related side effects and treatment burden compared to conventional IVF …

BACKGROUND Vitrification is a fast and effective method to cryopreserve ovarian tissue, but
it might influence mitochondrial activity and affect gene expression to cause persistent …

Oocyte health is tightly tied to mitochondria given their role in energy production, metabolite
supply, calcium (Ca 2+) buffering, and cell death regulation, among others. In turn …

Maternal age has a significant effect on oocyte developmental competence. Overall,
evidence suggests that oocytes from both prepubertal females and reproductively aged …

Aim The main goal of this study was to compare developmental competence and oxidative
status of vitrified‐warmed pre‐antral follicles (VPF) with pre‐antral follicles derived from …