Metabolic control of oocyte development

S Zhu, Q Wang - Biology of Reproduction, 2022 - academic.oup.com
Well balanced and timed metabolism is essential for oocyte development. The effects of
extrinsic nutrients on oocyte maturation have been widely reported. In contrast, intrinsic …

[HTML][HTML] The impact of alpha lipoic acid on developmental competence of mouse vitrified pre-antral follicles in comparison to those isolated from vitrified ovaries

S Hatami, S Zavareh, M Salehnia… - Iranian journal of …, 2014 - ncbi.nlm.nih.gov
Background: Cryopreservation of ovarian tissues and pre-antral follicles is a promising
prospect for preservation of women fertility. Objective: The aim of this study was to evaluate …

[HTML][HTML] β-hydroxybutyrate impairs bovine oocyte maturation via pyruvate dehydrogenase (PDH) associated energy metabolism abnormality

KY Zhang, J Guo, CL Zhan, CS Yuan, CG Min… - Frontiers in …, 2023 - frontiersin.org
Background: Ketosis is one of the most frequent and costly metabolic disorders in high-
producing dairy cows, and negatively associated with the health and reproductive …

Connexin 43 coupling in bovine cumulus cells, during the follicular growth phase, and its relationship to in vitro embryo outcomes

CC Read, G Willhelm, PW Dyce - Molecular Reproduction and …, 2018 - Wiley Online Library
Gap junctional coupling between cumulus cells is required for oocytes to reach
developmental competence. Multiple connexins, which form these gap junctions, have been …

[HTML][HTML] Chromatin as a sensor of metabolic changes during early development

D Pladevall-Morera, JJ Zylicz - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Cellular metabolism is a complex network of biochemical reactions fueling development with
energy and biomass; however, it can also shape the cellular epigenome. Indeed, some …

[HTML][HTML] Is placental mitochondrial function a regulator that matches fetal and placental growth to maternal nutrient intake in the mouse?

MR Chiaratti, S Malik, A Diot, E Rapa, L Macleod… - PloS one, 2015 - journals.plos.org
Background Effective fetal growth requires adequate maternal nutrition coupled to active
transport of nutrients across the placenta, which, in turn requires ATP. Epidemiological and …

[HTML][HTML] Dissection of the Ovulatory Process Using ex vivo Approaches

AA Tokmakov, VE Stefanov, KI Sato - Frontiers in cell and …, 2020 - frontiersin.org
Ovulation is a unique physiological phenomenon that is essential for sexual reproduction. It
refers to the entire process of ovarian follicle responses to hormonal stimulation resulting in …

Understanding oocyte ageing: can we influence the process as clinicians?

HA Homer - Current Opinion in Obstetrics and Gynecology, 2021 - journals.lww.com
Mitochondrial therapeutics such as NAD+-boosting used during the oocyte's growth phase
markedly improve oocyte quality in mice. Evaluating them in humans should focus on …

Oocyte-cumulus cells crosstalk: New comparative insights

CA Martinez, D Rizos, H Rodriguez-Martinez… - Theriogenology, 2023 - Elsevier
Mammalian follicles are constituted of a complex structure composed of several layers of
granulosa cells surrounding the oocyte and of theca cells that reside beneath its basement …

Sheep Isolated Secondary Follicles Are Able to Produce Metaphase II Oocytes After Vitrification and Long-Term In Vitro Growth

FO Lunardi, FLN de Aguiar, LB Apolloni… - Biopreservation and …, 2017 - liebertpub.com
The vitrification of preantral follicles followed by in vitro growth (IVG) could be valuable to
produce fertilizable oocytes. However, the meiotic resumption rates of oocytes cultured from …