Molecular dynamics simulations of membrane permeability

RM Venable, A Kramer, RW Pastor - Chemical reviews, 2019 - ACS Publications
This Review illustrates the evaluation of permeability of lipid membranes from molecular
dynamics (MD) simulation primarily using water and oxygen as examples. Membrane …

A review of progress in single particle tracking: from methods to biophysical insights

C Manzo, MF Garcia-Parajo - Reports on progress in physics, 2015 - iopscience.iop.org
Optical microscopy has for centuries been a key tool to study living cells with minimum
invasiveness. The advent of single molecule techniques over the past two decades has …

Brownian yet non-Gaussian diffusion: from superstatistics to subordination of diffusing diffusivities

AV Chechkin, F Seno, R Metzler, IM Sokolov - Physical Review X, 2017 - APS
A growing number of biological, soft, and active matter systems are observed to exhibit
normal diffusive dynamics with a linear growth of the mean-squared displacement, yet with a …

Polyploidy, the nucleotype, and novelty: the impact of genome doubling on the biology of the cell

JJ Doyle, JE Coate - International Journal of Plant Sciences, 2019 - journals.uchicago.edu
Polyploidy is a key mechanism of genome evolution and speciation, particularly in plants.
Many aspects of polyploidy have been elucidated with the tools that have become available …

[HTML][HTML] Bayesian deep learning for error estimation in the analysis of anomalous diffusion

H Seckler, R Metzler - Nature Communications, 2022 - nature.com
Modern single-particle-tracking techniques produce extensive time-series of diffusive motion
in a wide variety of systems, from single-molecule motion in living-cells to movement …

[HTML][HTML] Anomalous diffusion models and their properties: non-stationarity, non-ergodicity, and ageing at the centenary of single particle tracking

R Metzler, JH Jeon, AG Cherstvy… - Physical Chemistry …, 2014 - pubs.rsc.org
Modern microscopic techniques following the stochastic motion of labelled tracer particles
have uncovered significant deviations from the laws of Brownian motion in a variety of …

[HTML][HTML] A pH-driven transition of the cytoplasm from a fluid-to a solid-like state promotes entry into dormancy

MC Munder, D Midtvedt, T Franzmann, E Nuske, O Otto… - elife, 2016 - elifesciences.org
Cells can enter into a dormant state when faced with unfavorable conditions. However, how
cells enter into and recover from this state is still poorly understood. Here, we study …

[HTML][HTML] “Green” electronics: biodegradable and biocompatible materials and devices for sustainable future

M Irimia-Vladu - Chemical Society Reviews, 2014 - pubs.rsc.org
“Green” electronics represents not only a novel scientific term but also an emerging area of
research aimed at identifying compounds of natural origin and establishing economically …

[HTML][HTML] Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)

FX Theillet, A Binolfi, T Frembgen-Kesner… - Chemical …, 2014 - ACS Publications
It has long been axiomatic that a protein's structure determines its function. Intrinsically
disordered proteins (IDPs) and disordered protein regions (IDRs) defy this structure …

Protein crowding in lipid bilayers gives rise to non-Gaussian anomalous lateral diffusion of phospholipids and proteins

JH Jeon, M Javanainen, H Martinez-Seara, R Metzler… - Physical Review X, 2016 - APS
Biomembranes are exceptionally crowded with proteins with typical protein-to-lipid ratios
being around 1∶ 50− 1∶ 100. Protein crowding has a decisive role in lateral membrane …