Natural products derived from plants, as well as their bioactive compounds, have been
extensively studied in recent years for their therapeutic potential in a variety of …

Medicinal plants are well-known in affording clinically useful agents, with rich medicinal
values by combining with disease targets through various mechanisms. Plant secondary …

Dialkyl phthalates have been used as plasticizers in polymers for decades. As mobile, small
weight molecules, phthalates have entered the environment, where they have become …

Abstract β-Glucuronidase plays a vital role in the metabolism of drugs and endogenous
substance. Herein, we assayed the inhibitory effects of thirty-six flavonoids (1–36) toward β …

Mammalian carboxylesterases (CES), the key members of the serine hydrolase superfamily,
hydrolyze a wide range of endogenous substances and xenobiotics bearing ester or amide …

As the most important members of serine esterase hydrolase superfamily, mammalian
carboxylesterases (CESs) are widely distributed in various tissues like liver, intestine, lung …

Background Depression is a pervasive or persistent mental disorder that causes mood,
cognitive and memory deficits. Uncaria rhynchophylla has been widely used to treat central …

Natural soluble epoxide hydrolase inhibitors from Inula britanica and their potential interactions
with soluble epoxide hydrolase: Insight from inhibition kinetics and molecular dynamics …

Abstract Laportea bulbifera (Sieb. et. Zucc.) Wedd has long been utilized in Traditional
Chinese Medicines (TCM) for the treatment of rheumatoid arthritis. However, the study of …

Covering: 2008 to 2018 Over the last decade more than two hundred single natural products
were confirmed as natural allosteric modulators (alloNPs) of proteins. The compounds are …