Balance between the Cell Viability and Death in 3D

AC Debruyne, IA Okkelman, RI Dmitriev - Seminars in Cell & …, 2023 - Elsevier
Cell death is a phenomenon, frequently perceived as an absolute event for cell, tissue and
the organ. However, the rising popularity and complexity of such 3D multicellular 'tissue …

Live Microscopy of Multicellular Spheroids with the Multimodal Near-Infrared Nanoparticles Reveals Differences in Oxygenation Gradients

AC Debruyne, IA Okkelman, N Heymans, C Pinheiro… - ACS …, 2024 - ACS Publications
Assessment of hypoxia, nutrients, metabolite gradients, and other hallmarks of the tumor
microenvironment within 3D multicellular spheroid and organoid models represents a …

Bright and photostable TADF‐emitting zirconium (IV) pyridinedipyrrolide complexes: efficient dyes for decay time‐based temperature sensing and imaging

A Russegger, AC Debruyne, DC Berrio… - Advanced Optical …, 2023 - Wiley Online Library
Luminescence thermometry represents a technique of choice for measurements in small
objects and imaging of temperature distribution. However, most state‐of‐the‐art luminescent …

Highly sensitive ratiometric fluorescent fiber matrices for oxygen sensing with micrometer spatial resolution

G Grasso, V Onesto, S Forciniti, E D'Amone… - Bio-Design and …, 2024 - Springer
Abstract Oxygen (O2)-sensing matrices are promising tools for the live monitoring of
extracellular O2 consumption levels in long-term cell cultures. In this study, ratiometric O2 …

Highly sensitive detection of oxygen based on light-induced thermoelastic spectroscopy with a high power diode laser

R Wang, Y He, S Qiao, S Yang, Y Ma - Infrared Physics & Technology, 2024 - Elsevier
Oxygen (O 2) is a fundamental element in the atmosphere. It is important to detect it in
various fields. In this paper, a sensitive O 2 sensor based on light-induced thermoelastic …

Versatile, in-line optical oxygen tension sensors for continuous monitoring during ex vivo kidney perfusion

E Roussakis, JP Cascales, D Yoeli, A Cralley… - Sensors & …, 2024 - pubs.rsc.org
Integration of physiological sensing modalities within tissue and organ perfusion systems is
becoming a steadily expanding field of research, aimed at achieving technological …

Three-dimensional oxygen concentration monitoring in hydrogels using low-cost phosphorescence lifetime imaging for tissue engineering

X Mei, Q Fang, PR Selvaganapathy - Biomedical Optics Express, 2023 - opg.optica.org
Oxygen concentration measurement in 3D hydrogels is vital in 3D cell culture and tissue
engineering. However, standard 3D imaging systems capable of measuring oxygen …

[HTML][HTML] Prototyping in Polymethylpentene to Enable Oxygen-Permeable On-a-Chip Cell Culture and Organ-on-a-Chip Devices Suitable for Microscopy

L Sønstevold, P Koza, M Czerkies, E Andreassen… - Micromachines, 2024 - mdpi.com
With the rapid development and commercial interest in the organ-on-a-chip (OoC) field,
there is a need for materials addressing key experimental demands and enabling both …

Development of a fluidic platform for studying cancer cells under physiologically relevant oxygen conditions

AJG Lamb - 2023 - era.ed.ac.uk
In solid cancer tumours the oxygen concentration can be lower than in the corresponding
healthy tissue. This condition, known as hypoxia, impacts the behaviour and characteristics …