Bacterial Artificial Chromosome Reverse Genetics Approaches for SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new member of the
Coronaviridae family responsible for the coronavirus disease 19 (COVID-19) pandemic. To …
Coronaviridae family responsible for the coronavirus disease 19 (COVID-19) pandemic. To …
[HTML][HTML] Reverse genetics systems for SARS-CoV-2: Development and applications
HL Cai, YW Huang - Virologica Sinica, 2023 - Elsevier
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
caused serious harm to human health and struck a blow to global economic development …
caused serious harm to human health and struck a blow to global economic development …
[HTML][HTML] PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2
In search for broad-spectrum antivirals, we discovered a small molecule inhibitor, RMC-113,
that potently suppresses the replication of multiple RNA viruses including SARS-CoV-2 in …
that potently suppresses the replication of multiple RNA viruses including SARS-CoV-2 in …
[HTML][HTML] SARS-CoV-2 ORF3a drives dynamic dense body formation for optimal viral infectivity
S Hartmann, L Radochonski, C Ye… - Research …, 2024 - ncbi.nlm.nih.gov
SARS-CoV-2 uses the double-membrane vesicles as replication organelles. However, how
virion assembly occurs has not been fully understood. Here we identified a SARS-CoV-2 …
virion assembly occurs has not been fully understood. Here we identified a SARS-CoV-2 …
Monitoring SARS-CoV-2 infection using a double reporter-expressing virus
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the highly contagious
agent responsible for the coronavirus disease 2019 (COVID-19) pandemic. An essential …
agent responsible for the coronavirus disease 2019 (COVID-19) pandemic. An essential …
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for therapy
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to pose serious threats to …
respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to pose serious threats to …
Visualization of SARS-CoV-2 infection dynamic
Replication-competent recombinant viruses expressing reporter genes provide valuable
tools to investigate viral infection. Low levels of reporter gene expressed from previous …
tools to investigate viral infection. Low levels of reporter gene expressed from previous …
Using a reverse genetics system to generate recombinant SARS-CoV-2 expressing robust levels of reporter genes
C Ye, L Martinez-Sobrido - bioRxiv, 2022 - biorxiv.org
Reporter-expressing recombinant virus represents an excellent option and a powerful tool to
investigate, among others, viral infection, pathogenicity, and transmission, as well as to …
investigate, among others, viral infection, pathogenicity, and transmission, as well as to …
Generation and Applications of Reporter-Expressing Recombinant Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
K Chiem - 2023 - search.proquest.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
global pandemic of coronavirus disease 2019 (COVID-19), causing over 6.6 million deaths …
global pandemic of coronavirus disease 2019 (COVID-19), causing over 6.6 million deaths …