Carbapenemases are β-lactamases belonging to different Ambler classes (A, B, D) and can
be encoded by both chromosomal and plasmid-mediated genes. These enzymes represent …

Acinetobacter is a complex genus, and historically, there has been confusion about the
existence of multiple species. The species commonly cause nosocomial infections …

Antibiotic resistance is a major global public health concern. Acinetobacter baumannii is a
nosocomial pathogen that has emerged as a global threat because of its high levels of …

Acinetobacter baumannii is considered one of the most persistent pathogens responsible for
nosocomial infections. Due to the emergence of multidrug resistant strains, as well as high …

Plasmids found in Acinetobacter species contribute to the spread of antibiotic resistance
genes. They appear to be largely confined to this genus and cannot be typed with available …

The oxa23 gene encoding the OXA-23 carbapenemase (and several minor variants of it) is
widespread in Acinetobacter baumannii clinical isolates and compromises treatment with …

Horizontal gene transfer (HGT) is a driving force to the evolution of bacteria. The fast
emergence of antimicrobial resistance reflects the ability of genetic adaptation of pathogens …

The worldwide spread of carbapenem-resistant Acinetobacter baumannii (CRAB) has
become a healthcare challenge for some decades. To understand its molecular …

Background To investigate the carbapenem resistance mechanisms and clonal relationship
of carbapenem-resistant Acinetobacter baumannii (CRAB) strains isolated in the intensive …

Carbapenem-resistant Acinetobacter baumannii (CRAB) presents a serious therapeutic and
infection control challenge. In this study, we investigated the epidemiological and molecular …