Metabolic changes are coupled with alteration in protein glycosylation. In this review, we will
focus on macrophages that are pivotal in the pathogenesis of pulmonary fibrosis and …

Metabolic reprogramming underlies the etiology and pathophysiology of respiratory
diseases such as asthma, idiopathic pulmonary fibrosis (IPF), and chronic obstructive …

Importance Current treatments for idiopathic pulmonary fibrosis slow the rate of lung function
decline, but may be associated with adverse events that affect medication adherence. In …

Evidence indicates that metabolic reprogramming characterized by the changes in cellular
metabolic patterns contributes to the pathogenesis of pulmonary fibrosis (PF). It is …

Background Numerous metabolomic studies have confirmed the pivotal role of metabolic
abnormalities in the development of idiopathic pulmonary fibrosis (IPF). Nevertheless, there …

Pulmonary fibrosis (PF) can be idiopathic or driven by a specific insult or disease process.
Inflammation plays a role in the pathophysiology, the extent of which remains a longstanding …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrotic interstitial lung diseases,
which mainly existed in middle-aged and elderly people. The accumulation of reactive …

Silicosis, recognized as a severe global public health issue, is an irreversible pulmonary
fibrosis caused by the long-term inhalation of silica particles. Given the intricate …

Pulmonary fibrosis (PF) is a chronic progressive end-stage lung disease. However, the
mechanisms underlying the progression of this disease remain elusive. Presently, clinically …

Osteoarthritis (OA), a chronic degenerative joint disease, is the most common form of
arthritis. OA occurs when the protective cartilage that cushions the ends of bones gradually …