Crosstalk between inflammation and hemorrhage/coagulation disorders in primary blast lung injury

J Li, J Zhang, M Shi, S Yu, M Ji, Y Liang, X Meng - Biomolecules, 2023 - mdpi.com
Primary blast lung injury (PBLI), caused by exposure to high-intensity pressure waves from
explosions in war, terrorist attacks, industrial production, and life explosions, is associated …

Effects and mechanisms of extremely cold environment on body response after trauma

YY Peng, XM Lu, S Li, C Tang, Y Ding, HY Wang… - Journal of Thermal …, 2023 - Elsevier
With the outbreak of the Ukrainian crisis, extremely cold environment warfare has once
again become the focus of international attention. People exposed to extremely cold …

Impact of platelets and platelet-derived microparticles on hypercoagulability following burn injury

EF Midura, JW Kuethe, TC Rice, R Veile, LG England… - Shock, 2016 - journals.lww.com
An acute burn induced coagulopathy develops after scald injury, which evolves into a
subacute, hypercoagulable state. Microparticles, specifically platelet-derived MPs (PMPs) …

[HTML][HTML] Platelet priming and activation in naturally occurring thermal burn injuries and wildfire smoke exposure is associated with intracardiac thrombosis and …

AWK Tan, RHL Li, Y Ueda, JA Stern… - Frontiers in Veterinary …, 2022 - frontiersin.org
Wildfires pose a major health risk for humans, wildlife, and domestic animals. We previously
discovered pathophysiologic parallels between domestic cats with naturally occurring …

Comprehensive evaluation of coagulation in swine subjected to isolated primary blast injury

NJ Prat, R Montgomery, AP Cap, MA Dubick, JC Sarron… - Shock, 2015 - journals.lww.com
Blast is one of the major causes of injury and death in recent armed conflicts. With increased
use of improvised explosive devices in Iraq and Afghanistan, more than 71% of combat …

Platelet and coagulation function before and after burn and smoke inhalation injury in sheep

NJ Prat, MC Herzig, S Kreyer… - Journal of Trauma …, 2017 - journals.lww.com
BACKGROUND Smoke inhalation and burn injury remain a major source of morbidity and
mortality. There is known dysregulation of hemostasis in burn patients, but either …

A natural history study of coagulopathy in a porcine 40% total body surface area burn model reveals the time-dependent significance of functional assays

MM McDonough, J Keyloun, T Orfeo… - Burns, 2022 - Elsevier
Various studies have reported discordant results on the magnitude and direction of burn-
induced coagulopathy (BIC), which has recently been associated with multiple organ …

Cellular mechanisms and behavioral outcomes in blast-induced neurotrauma: comparing experimental setups

ZS Bailey, WB Hubbard, PJ VandeVord - Injury Models of the Central …, 2016 - Springer
Blast-induced neurotrauma (BINT) has increased in incidence over the past decades and
can result in cognitive issues that have debilitating consequences. The exact primary and …

[HTML][HTML] Examining lethality risk for rodent studies of primary blast lung injury

WB Hubbard, C Hall, VSSS Sajja, E Lavik… - Biomedical sciences …, 2014 - ncbi.nlm.nih.gov
While protective measures have been taken to mitigate injury to the thorax during a blast
exposure, primary blast lung injury (PBLI) is still evident in mounted/in vehicle cases during …

Bridging the gap of standardized animals models for blast neurotrauma: methodology for appropriate experimental testing

PJ VandeVord, ADC Leonardi, D Ritzel - Injury Models of the Central …, 2016 - Springer
Recent military combat has heightened awareness to the complexity of blast-related
traumatic brain injuries (bTBI). Experiments using animal, cadaver, or biofidelic physical …