Structural changes involving tissue remodelling and fibrosis are major features of many
pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD) and …

Endothelial dysfunction is a major contributing factor to diseases such as atherosclerosis,
diabetes mellitus, obesity, hypertension, acute lung injury, preeclampsia, among others …

Chronic obstructive pulmonary disease (COPD) is one of the most common chronic
respiratory diseases with high morbidity and mortality. It has become the fifth most burdened …

Pulmonary fibrosis (PF) is characterised by several grades of chronic inflammation and
collagen deposition in the interalveolar space and is a hallmark of interstitial lung diseases …

Endothelial to mesenchymal transition: a precursor to post-COVID-19 interstitial pulmonary
fibrosis and vascular obliteration? | European Respiratory Society Skip to main content Main …

COVID-19 is a highly contagious respiratory disease, which mainly affects the lungs.
Critically ill patients are easily complicated by cytokine storms, acute respiratory distress …

Background Pulmonary hypertension (PH) associated to idiopathic pulmonary fibrosis (IPF)
portends a poor prognosis. IL-11 has been implicated in fibrotic diseases, but their role on …

Pulmonary hypertension (PH) is a chronic and fatal disease, for which new therapeutic
drugs and approaches are needed urgently. Baicalein and baicalin, the active compounds …

Background We have previously reported arterial remodelling in patients with idiopathic
pulmonary fibrosis (IPF) and suggested that endothelial-to-mesenchymal transition (EndMT) …

The glycosylation of cell surface receptors has been shown to regulate each step of signal
transduction, including receptor trafficking to the cell surface, ligand binding, dimerization …