The long and short non-coding RNAs modulating EZH2 signaling in cancer

S Mirzaei, MH Gholami, K Hushmandi… - Journal of hematology & …, 2022 - Springer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …

Small in size, but large in action: microRNAs as potential modulators of PTEN in breast and lung cancers

AJ Abadi, A Zarrabi, MH Gholami, S Mirzaei… - Biomolecules, 2021 - mdpi.com
MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …

[HTML][HTML] Stage-specific treatment of colorectal cancer: A microRNA-nanocomposite approach

AO Fadaka, T Akinsoji, A Klein, AM Madiehe… - Journal of …, 2023 - Elsevier
Colorectal cancer (CRC) is among the leading causes of cancer mortality. The lifetime risk of
developing CRC is about 5% in adult males and females. CRC is usually diagnosed at an …

Endothelial miR-196b-5p regulates angiogenesis via the hypoxia/miR-196b-5p/HMGA2/HIF1α loop

R Ren, K Ma, Y Jiang, J Chen, Y Kou… - … of Physiology-Cell …, 2023 - journals.physiology.org
Angiogenesis is involved in development, reproduction, wound healing, homeostasis, and
other pathophysiological events. Imbalanced angiogenesis predisposes patients to various …

MiR‐223 Promotes Tumor Progression via Targeting RhoB in Gastric Cancer

Y Hu, B Yi, X Chen, L Xu, X Zhou, X Zhu - Journal of Oncology, 2022 - Wiley Online Library
Gastric cancer (GC) is among the most prevalent causes of cancer‐related death globally.
MiR‐223 has been implicated in a variety of cellular mechanisms linked to cancer …

MiRNA‐196‐5p Promotes Proliferation and Migration in Cholangiocarcinoma via HAND1/Wnt/β‐Catenin Signaling Pathway

C Liu, Y Li, L Zhang, P Zhang, N Yu, X Liu… - Journal of …, 2022 - Wiley Online Library
Accumulating evidence has indicated the crucial role of microRNA‐196 in mediating tumor
progression, while its significance in cholangiocarcinoma (CCA) remains unclear. In this …

The roles of ING5 in cancer: A tumor suppressor

H Zheng, H Xue, H Jiang - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
As a Class II tumor suppressor, ING5 contains nuclear localization signal, plant
homeodomain, novel conserved region, and leucine zipper-like domains. ING5 proteins …

Systemic investigation identifying salivary miR-196b as a promising biomarker for early detection of head-neck cancer and oral precancer lesions

AJ Cheng, GR You, CJ Lee, YC Lu, SJ Tang, YF Huang… - Diagnostics, 2021 - mdpi.com
Background: Liquid biopsy is a rapidly growing field, for it may provide a minimally invasive
way to acquire pathological data for personalized medicine. This study developed a …

Hypermethylation of MGMT Gene Promoter in Peripheral Blood Mononuclear Cells as a Noninvasive Biomarker for Colorectal Cancer Diagnosis

S Azhdari, F Khodabandehloo… - Advanced Biomedical …, 2023 - journals.lww.com
Background: Early colorectal cancer (CRC) diagnosis can drastically reduce CRC-related
morbidity and mortality. In this regard, increasing attention is now being directed to DNA …

miR-196a-5p correlates with chronic atrophic gastritis progression to gastric cancer and induces malignant biological behaviors of gastric cancer cells by targeting …

J Zheng, X Jiang, K Jiang, Y Yan, J Pan, F Liu… - Molecular …, 2023 - Springer
Background As the prognosis of early gastric cancer (EGC) is significantly better than that of
advanced gastric cancer (AGC), the development of biomarkers to monitor the progression …