Acute ischemic stroke is a common cause of morbidity and mortality worldwide.
Thrombolysis with recombinant tissue plasminogen activator and endovascular …

The NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells) transcription factor
family is a pleiotropic regulator of many cellular signaling pathways, providing a mechanism …

Inflammation occurs as a result of exposure of tissues and organs to harmful stimuli such as
microbial pathogens, irritants, or toxic cellular components. The primary physical …

Astrocytes are the most abundant cell type within the central nervous system. They play
essential roles in maintaining normal brain function, as they are a critical structural and …

Aging is the main risk factor for neurodegenerative diseases. In aging, microglia undergoes
phenotypic changes compatible with their activation. Glial activation can lead to …

Stroke is the second leading cause of death, after ischemic heart disease, and accounts for
9% of deaths worldwide. According to the World Health Organization [WHO], 15 million …

Aging is the leading risk factor for several age-associated diseases such as
neurodegenerative diseases. Understanding the biology of aging mechanisms is essential …

Different animal and human studies from last two decades in the case of Parkinson's
disease (PD) have concentrated on oxidative stress due to increased inflammation and …

Parkinson's disease (PD) is the second most common neurodegenerative disease, after
Alzheimer's disease. The potential causes of PD remain uncertain, but recent studies …

Inflammation can cause damage and even death. What controls this primitive and potentially
lethal innate immune response to injury and infection? Molecular and neurophysiological …