Off‐label underdosing of four individual NOACs in patients with nonvalvular atrial fibrillation: A systematic review and meta‐analysis of observational studies

C Sang, J Chen, J Sun, Y Lai, X Liu… - European Journal of …, 2022 - Wiley Online Library
Background Although several meta‐analyses have examined the effects of off‐label
underdosing of nonvitamin K antagonist oral anticoagulants (NOACs) compared with their …

Important risk factors in patients with nonvalvular atrial fibrillation taking dabigatran using integrated machine learning scheme—a post hoc analysis

YC Huang, YC Cheng, MJ Jhou, M Chen… - Journal of Personalized …, 2022 - mdpi.com
Our study aims to develop an effective integrated machine learning (ML) scheme to predict
vascular events and bleeding in patients with nonvalvular atrial fibrillation taking dabigatran …

Potentially inappropriate prescribing in multimorbid and polymedicated older adults with AF: A Systematic Review and Meta-Analysis

C Amrouch, D Vauterin, S Amrouch, M Grymonprez… - Drugs & Aging, 2024 - Springer
Aim Polypharmacy in multimorbid older patients with atrial fibrillation (AF) is a risk factor for
potentially inappropriate prescribing (PIP). We aimed to systematically assess the evidence …

Direct oral anticoagulant (DOAC) dosing in patients with non-valvular atrial fibrillation (NVAF) in the United Kingdom: a retrospective cohort study using CPRD Gold …

A Khachatryan, IU Doobaree, G Spentzouris… - Advances in …, 2023 - Springer
Introduction Per-label dosing of direct oral anticoagulants (DOACs) is important for the
prevention of stroke and systemic embolism among patients with non-valvular atrial …

The stroke enigma: decoding the sex risk factor in atrial fibrillation

ME Middeldorp, RK Sandhu - European Heart Journal, 2024 - academic.oup.com
Important sex differences exist in the epidemiology and outcomes of atrial fibrillation (AF),
the most common sustained arrhythmia encountered in clinical practice. 1 Although the …

[PDF][PDF] Association between genetic polymorphisms in fibrinogen genes and bleeding risk in patients treated with direct oral anticoagulants

KH Choi, J Yee, TJ Song, J Park, HS Gwak - Ann Acad Med Singap, 2023 - annals.edu.sg
Introduction: This study aimed to investigate the association between polymorphisms in
fibrinogen genes and bleeding risk in patients receiving direct oral anticoagulants (DOACs) …

Implementation of a pharmacist-developed, indication-based order panel for outpatient prescribing of direct-acting oral anticoagulants

C Trueman, E Langenhan, L Dunn… - American Journal of …, 2024 - academic.oup.com
Disclaimer In an effort to expedite the publication of articles, AJHP is posting manuscripts
online as soon as possible after acceptance. Accepted manuscripts have been peer …

Phenotype-directed clinically driven low-dose direct oral anticoagulant for atrial fibrillation

TW Kao, PJ Liao - Future Cardiology, 2023 - Taylor & Francis
Clinically-driven dose reduction of direct oral anticoagulants in individuals with atrial
fibrillation is prevalent worldwide. However, a paucity of evidence to tailor dose selection …

Antithrombotische Therapie

H Wille - Arzneiverordnungs-Report 2023, 2024 - Springer
Zusammenfassung Auf einen Blick Trend Die Gesamtverordnungen der
Thrombozytenaggregationshemmer sind 2022 gegenüber dem Vorjahr gering gesunken …

非弁膜症性心房細動における脳塞栓予防デバイス: 経皮的左心耳閉鎖システム(WATCHMANTM)

山脇理弘, 酒井毅, 笠井陽介 - 心臓, 2022 - jstage.jst.go.jp
抄録 非弁膜症性心房細動 (NVAF) において, 左心耳血栓は心原性脳梗塞の最大要因である.
直接経口抗凝固薬 (DOAC) は, ワルファリンに比較して, 非劣性または優越性な全身塞栓予防効果 …