In the last decades, antimicrobial resistance has become a global threat to public health
systems worldwide. Among those bacteria that pose the greatest threat to human health …

Escherichia coli ST131emerged during the early to mid-2000s is an important human
pathogen, has spread extensively throughout the world, and is responsible for the rapid …

Hypervirulence and carbapenem-resistant have emerged as two distinct evolutionary
pathotypes of Klebsiella pneumoniae, with both reaching their epidemic success and posing …

Rapid identification of patients who are colonized with carbapenemase-producing
organisms (CPO) is included in multiple national guidelines for containment of these …

En la actualidad, la diseminación de enterobacterias productoras de carbapenemasas se
considera un grave problema en clínica debido al fracaso en el tratamiento de las …

Introduction Carbapenemases are β-lactamases able to hydrolyze a wide range of β-lactam
antibiotics, including carbapenems. Carbapenemase production in Enterobacterales …

Introduction KPC carbapenemase-producing Klebsiella pneumoniae (KPC-KP) has become
a major public health challenge. Accordingly, this study sought to use a systematic review of …

Carbapenemases have become a significant mechanism for broad-spectrum β-lactam
resistance in Enterobacteriaceae and other Gram-negative bacteria such as Pseudomonas …

A review of the literature was undertaken to delineate the current level and mechanisms of
resistance to carbapenems, colistin, and tigecycline in South Africa. Thirty-two English …

After an increase in carbapenem-resistant Klebsiella pneumoniae (CRKP) bloodstream
infections and associated deaths in the neonatal unit of a South Africa hospital, we …