Overexpression of semaphorin 4D (SEMA4D), an immune semaphorin, is found in various
human malignancies, including colorectal cancer (CRC). In this study, we explored the …

Objectives. Chemotherapy is considered to be essential in the treatment of patients with
colorectal cancer (CRC), but drug resistance reduces its efficacy. Many patients with …

Purpose: Colorectal cancer (CRC) is a frequent fatal cancer worldwide. 5-Fluorouracil (5-
FU) is extensively used in chemotherapy. Its drug resistance, however, should be well …

Background: Cancer remains to be a major health problem despite advances in treatment.
Chemo-and radiotherapy resistance accounting for cancer recurrence have been recently …

Fibroblasts in the stroma play a critical role in tumor evolution. In this study, we assessed the
influence of colonic fibroblasts on colon cancer cells treated with 5‐fluorouracil (5‐FU), and …

Despite improvements in prevention and treatment approaches, colorectal cancer (CRC) still
remains a highly life-threatening disease worldwide. The formation of metastasis, in …

Background Colorectal cancer (CRC) has high mortality, and 5-fluorouracil (5-FU) is a
common clinical chemotherapeutic drug. The current study aimed to investigate the role of …

Objectives The skin has a high demand for folates because of its constant renewal and
growth. Folates play an important role in the metabolism of healthy skin and in the …

Since the beginning of the SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2)
pandemic, a race to develop a vaccine has been initiated, considering the massive and …