Evidence has suggested that parental age at birth is a risk factor of offspring attention
deficit/hyperactivity disorder (ADHD). We conducted a meta-analysis of observational …

Importance Advanced parental age has been associated with autism spectrum disorders
(ASDs) in children. However, little is known about the association between grandparental …

Because the assessment of sperm DNA fragmentation (SDF) plays a key role in male fertility,
our study was designed to find the relationships between SDF and standard semen …

The elderly males undergo degenerative fertility and testicular endocrine function that
jeopardize the reproductive health and well-being. However, the mechanisms underlying …

STUDY QUESTION Is the use of ART, a proxy for infertility, associated with epigenetic age
acceleration? SUMMARY ANSWER The epigenetic age acceleration measured by Dunedin …

Existen más de 10 000 enfermedades genéticas descritas en el mundo y afectan alrededor
del 7% de la población mundial, causando alta morbimortalidad y costos para los sistemas …

The age-associated imbalances between proliferation and apoptosis lead to impaired
spermatogenesis and infertility. The age-associated decline in vitamin D3 levels has been …

BACKGROUND There is a global tendency for parents to conceive children later in life. The
maternal dimension of the postponement transition has been thoroughly studied, but interest …

Ageing is a gradual and multi-factorial process with a significant impact on fertility. The
mechanism of declined testicular functions with age remains elusive. Asprosin is a novel …

Although DNA methylation variation of autosomal CpGs provides robust age predictive
biomarkers, no male-specific age predictor exists based on Y-CpGs yet. Since sex …