[HTML][HTML] Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options

JCO Sardi, L Scorzoni, T Bernardi… - Journal of medical …, 2013 - microbiologyresearch.org
The incidence of fungal infections has increased significantly, so contributing to morbidity
and mortality. This is caused by an increase in antimicrobial resistance and the restricted …

Multimetal resistance and tolerance in microbial biofilms

JJ Harrison, H Ceri, RJ Turner - Nature Reviews Microbiology, 2007 - nature.com
Geochemical cycling and industrial pollution have made toxic metal ions a pervasive
environmental pressure throughout the world. Biofilm formation is a strategy that …

[HTML][HTML] A Candida Biofilm-Induced Pathway for Matrix Glucan Delivery: Implications for Drug Resistance

HT Taff, JE Nett, R Zarnowski, KM Ross, H Sanchez… - 2012 - journals.plos.org
Extracellular polysaccharides are key constituents of the biofilm matrix of many
microorganisms. One critical carbohydrate component of Candida albicans biofilms, β-1, 3 …

Community participation in biofilm matrix assembly and function

KF Mitchell, R Zarnowski, H Sanchez… - Proceedings of the …, 2015 - National Acad Sciences
Biofilms of the fungus Candida albicans produce extracellular matrix that confers such
properties as adherence and drug resistance. Our prior studies indicate that the matrix is …

An extracellular matrix glues together the aerial‐grown hyphae of Aspergillus fumigatus

A Beauvais, C Schmidt, S Guadagnini… - Cellular …, 2007 - Wiley Online Library
Pulmonary infections due to Aspergillus fumigatus result from the development of a colony of
tightly associated hyphae in contact with the air, either in the alveoli (invasive aspergillosis) …

Candida albicans biofilm development, modeling a host–pathogen interaction

J Nett, D Andes - Current opinion in microbiology, 2006 - Elsevier
Medical device-associated infections involve the attachment of cells to a surface, production
of an extracellular matrix and development of a mature biofilm. Many Candida albicans …

Interface of Candida albicans biofilm matrix-associated drug resistance and cell wall integrity regulation

JE Nett, H Sanchez, MT Cain, KM Ross… - Eukaryotic cell, 2011 - Am Soc Microbiol
Candida albicans frequently infects medical devices by growing as a biofilm, ie, a
community of adherent organisms entrenched in an extracellular matrix. During biofilm …

Optimizing a Candida biofilm microtiter plate model for measurement of antifungal susceptibility by tetrazolium salt assay

JE Nett, MT Cain, K Crawford… - Journal of clinical …, 2011 - Am Soc Microbiol
Candida spp. infect medical devices, such as venous and urinary catheters, by adhering to
the surface and forming a community of drug-resistant cells surrounded by a matrix. The …

[HTML][HTML] Antifungal Activity and Potential Mechanism of N-Butylphthalide Alone and in Combination With Fluconazole Against Candida albicans

Y Gong, W Liu, X Huang, L Hao, Y Li… - Frontiers in microbiology, 2019 - frontiersin.org
Candida albicans is a common opportunistic fungal pathogen that may cause nosocomial
fungal infections. The resistance of Candida albicans to traditional antifungal drugs has …

Biofilm Formation by and Antifungal Susceptibility of Candida Isolates from Urine

N Jain, R Kohli, E Cook, P Gialanella… - Applied and …, 2007 - Am Soc Microbiol
Biofilm formation (BF) in the setting of candiduria has not been well studied. We determined
BF and MIC to antifungals in Candida spp. isolates grown from urine samples of patients …