Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

Increasing public awareness of foodborne illnesses, factory farming, and the ecological
footprint of the meat industry, has generated the need for animal-free meat alternatives. In …

Muscle regeneration relies on the regulation of muscle stem cells (MuSCs) through
paracrine signaling interactions. We analyzed muscle regeneration in mice using single-cell …

The loss of skeletal muscle mass under a wide range of acute and chronic maladies is
associated with poor prognosis, reduced quality of life, and increased mortality. Decades of …

Tissue injury initiates a complex repair process, which in some organisms can lead to the
complete regeneration of a tissue. In mammals, however, the repair of most organs is …

Single-cell RNA-sequencing (scRNA-seq) facilitates the unbiased reconstruction of
multicellular tissue systems in health and disease. Here, we present a curated scRNA-seq …

The emerging field of cultured meat faces several technical hurdles, including the scale-up
production of quality muscle and adipose progenitor cells, and the differentiation and …

The extracellular matrix (ECM) is an interconnected macromolecular scaffold occupying the
space between cells. Amongst other functions, the ECM provides structural support to …

Sarcopenia refers to the gradual loss of skeletal muscle mass and function along with aging
and is a social burden due to growing healthcare cost associated with a super-aging society …

Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength,
and functions in elderly people. It is accompanied by physical frailty, functional disability …