[HTML][HTML] Advances in protein-protein interaction network analysis for Parkinson's disease
JE Tomkins, C Manzoni - Neurobiology of Disease, 2021 - Elsevier
Protein-protein interactions (PPIs) are a key component of the subcellular molecular
networks which enable cells to function. Due to their importance in homeostasis, alterations …
networks which enable cells to function. Due to their importance in homeostasis, alterations …
The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
A system-wide understanding of cellular function requires knowledge of all functional
interactions between the expressed proteins. The STRING database aims to collect and …
interactions between the expressed proteins. The STRING database aims to collect and …
The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins
AD Rouillard, GW Gundersen, NF Fernandez… - Database, 2016 - academic.oup.com
Genomics, epigenomics, transcriptomics, proteomics and metabolomics efforts rapidly
generate a plethora of data on the activity and levels of biomolecules within mammalian …
generate a plethora of data on the activity and levels of biomolecules within mammalian …
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
Background System-wide profiling of genes and proteins in mammalian cells produce lists of
differentially expressed genes/proteins that need to be further analyzed for their collective …
differentially expressed genes/proteins that need to be further analyzed for their collective …
Lean Big Data integration in systems biology and systems pharmacology
Data sets from recent large-scale projects can be integrated into one unified puzzle that can
provide new insights into how drugs and genetic perturbations applied to human cells are …
provide new insights into how drugs and genetic perturbations applied to human cells are …
Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis
E Flex, M Jaiswal, F Pantaleoni… - Human molecular …, 2014 - academic.oup.com
RASopathies, a family of disorders characterized by cardiac defects, defective growth, facial
dysmorphism, variable cognitive deficits and predisposition to certain malignancies, are …
dysmorphism, variable cognitive deficits and predisposition to certain malignancies, are …
Merging in-silico and in vitro salivary protein complex partners using the STRING database: a tutorial
Protein-protein interaction is a common physiological mechanism for protection and actions
of proteins in an organism. The identification and characterization of protein-protein …
of proteins in an organism. The identification and characterization of protein-protein …
Toxicology knowledge graph for structural birth defects
Background Birth defects are functional and structural abnormalities that impact about 1 in
33 births in the United States. They have been attributed to genetic and other factors such as …
33 births in the United States. They have been attributed to genetic and other factors such as …
Construction and analysis of the protein-protein interaction networks based on gene expression profiles of Parkinson's disease
Background Parkinson's Disease (PD) is one of the most prevailing neurodegenerative
diseases. Improving diagnoses and treatments of this disease is essential, as currently there …
diseases. Improving diagnoses and treatments of this disease is essential, as currently there …
Detection of candidate biomarkers of prostate cancer progression in serum: a depletion-free 3D LC/MS quantitative proteomics pilot study
SET Larkin, HE Johnston, TR Jackson… - British journal of …, 2016 - nature.com
Background: Prostate cancer (PCa) is the most common male cancer in the United Kingdom
and we aimed to identify clinically relevant biomarkers corresponding to stage progression …
and we aimed to identify clinically relevant biomarkers corresponding to stage progression …