Chemical design of activatable photoacoustic probes for precise biomedical applications

Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …

[HTML][HTML] Immunology of wound healing

S Ellis, EJ Lin, D Tartar - Current dermatology reports, 2018 - Springer
Abstract Purpose of Review Chronic wounds are a tremendous burden on the healthcare
system and lead to significant patient morbidity and mortality. Normal cutaneous wound …

Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin–N-cadherin pathway after spinal cord injury

M Hara, K Kobayakawa, Y Ohkawa, H Kumamaru… - Nature medicine, 2017 - nature.com
Central nervous system (CNS) injury transforms naive astrocytes into reactive astrocytes,
which eventually become scar-forming astrocytes that can impair axonal regeneration and …

Antitumor polysaccharides from mushrooms: a review on the structural characteristics, antitumor mechanisms and immunomodulating activities

X Meng, H Liang, L Luo - Carbohydrate research, 2016 - Elsevier
Mushrooms are popular folk medicines that have attracted considerable attention because
of their efficient antitumor activities. This review covers existing research achievements on …

[HTML][HTML] Happily (n) ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence

A Höhn, D Weber, T Jung, C Ott, M Hugo, B Kochlik… - Redox biology, 2017 - Elsevier
Aging is a complex phenomenon and its impact is becoming more relevant due to the rising
life expectancy and because aging itself is the basis for the development of age-related …

Molecular mechanisms and clinical applications of angiogenesis

P Carmeliet, RK Jain - Nature, 2011 - nature.com
Blood vessels deliver oxygen and nutrients to every part of the body, but also nourish
diseases such as cancer. Over the past decade, our understanding of the molecular …

[HTML][HTML] Basic and therapeutic aspects of angiogenesis

M Potente, H Gerhardt, P Carmeliet - Cell, 2011 - cell.com
Blood vessels form extensive networks that nurture all tissues in the body. Abnormal vessel
growth and function are hallmarks of cancer and ischemic and inflammatory diseases, and …

RAS oncogenes: weaving a tumorigenic web

Y Pylayeva-Gupta, E Grabocka, D Bar-Sagi - Nature Reviews Cancer, 2011 - nature.com
RAS proteins are essential components of signalling pathways that emanate from cell
surface receptors. Oncogenic activation of these proteins owing to missense mutations is …

The senescence-associated secretory phenotype: the dark side of tumor suppression

JP Coppé, PY Desprez, A Krtolica… - Annual review of …, 2010 - annualreviews.org
Cellular senescence is a tumor-suppressive mechanism that permanently arrests cells at
risk for malignant transformation. However, accumulating evidence shows that senescent …

Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis

C Wei, S El Hindi, J Li, A Fornoni, N Goes… - Nature medicine, 2011 - nature.com
Focal segmental glomerulosclerosis (FSGS) is a cause of proteinuric kidney disease,
compromising both native and transplanted kidneys. Treatment is limited because of a …