Engineering cell membrane‐based nanotherapeutics to target inflammation

H Yan, D Shao, YH Lao, M Li, H Hu… - Advanced …, 2019 - Wiley Online Library
Inflammation is ubiquitous in the body, triggering desirable immune response to defend
against dangerous signals or instigating undesirable damage to cells and tissues to cause …

[HTML][HTML] Plasticity of cancer invasion and energy metabolism

M Parlani, C Jorgez, P Friedl - Trends in cell biology, 2023 - cell.com
Energy deprivation is a frequent adverse event in tumors that is caused by mutations,
malperfusion, hypoxia, and nutrition deficit. The resulting bioenergetic stress leads to …

Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells

A Hayer, L Shao, M Chung, LM Joubert, HW Yang… - Nature cell …, 2016 - nature.com
The development and maintenance of tissues requires collective cell movement, during
which neighbouring cells coordinate the polarity of their migration machineries. Here, we …

Imaging cell‐matrix adhesions and collective migration of living cells by electrochemiluminescence microscopy

H Ding, W Guo, B Su - Angewandte Chemie International …, 2020 - Wiley Online Library
Cell‐matrix adhesions play essential roles in a variety of biological processes. Herein, we
report a label‐free method to map cell‐matrix adhesions of single living cells on an …

Recent advances in mesenchymal stem cell membrane-coated nanoparticles for enhanced drug delivery

M Wang, Y Xin, H Cao, W Li, Y Hua, TJ Webster… - Biomaterials …, 2021 - pubs.rsc.org
Studies of nanomedicine have achieved dramatic progress in recent decades. However, the
main challenges that traditional nanomedicine has to overcome include low accumulation at …

[HTML][HTML] Extracellular vesicles: Critical players during cell migration

BH Sung, CA Parent, AM Weaver - Developmental cell, 2021 - cell.com
Cell migration is essential for the development and maintenance of multicellular organisms,
contributing to embryogenesis, wound healing, immune response, and other critical …

Rac1: A regulator of cell migration and a potential target for cancer therapy

N Ma, E Xu, Q Luo, G Song - Molecules, 2023 - mdpi.com
Cell migration is crucial for physiological and pathological processes such as
morphogenesis, wound repair, immune response and cancer invasion/metastasis. There are …

Active wetting of epithelial tissues

C Pérez-González, R Alert, C Blanch-Mercader… - Nature physics, 2019 - nature.com
Abstract Development, regeneration and cancer involve drastic transitions in tissue
morphology. In analogy with the behaviour of inert fluids, some of these transitions have …

Mechanical interactions among followers determine the emergence of leaders in migrating epithelial cell collectives

M Vishwakarma, J Di Russo, D Probst… - Nature …, 2018 - nature.com
Regulating the emergence of leaders is a central aspect of collective cell migration, but the
underlying mechanisms remain ambiguous. Here we show that the selective emergence of …

Development and dynamics of cell polarity at a glance

JP Campanale, TY Sun, DJ Montell - Journal of cell science, 2017 - journals.biologists.com
Cells exhibit morphological and molecular asymmetries that are broadly categorized as cell
polarity. The cell polarity established in early embryos prefigures the macroscopic …