Cell spheroid fusion: beyond liquid drops model

NV Kosheleva, YM Efremov, BS Shavkuta, IM Zurina… - Scientific reports, 2020 - nature.com
Biological self-assembly is crucial in the processes of development, tissue regeneration, and
maturation of bioprinted tissue-engineered constructions. The cell aggregates—spheroids …

Cancer metastasis: a reappraisal of its underlying mechanisms and their relevance to treatment

N Riggi, M Aguet, I Stamenkovic - Annual Review of Pathology …, 2018 - annualreviews.org
Metastases are responsible for the vast majority of cancer-related deaths, but, despite
intense efforts to understand their underlying mechanisms with the goal of uncovering …

Maneuvering the migration and differentiation of stem cells with electrospun nanofibers

J Xue, D Pisignano, Y Xia - Advanced Science, 2020 - Wiley Online Library
Electrospun nanofibers have been extensively explored as a class of scaffolding materials
for tissue regeneration, because of their unique capability to mimic some features and …

[HTML][HTML] Adjustable viscoelasticity allows for efficient collective cell migration

EH Barriga, R Mayor - Seminars in cell & developmental biology, 2019 - Elsevier
Cell migration is essential for a wide range of biological processes such as embryo
morphogenesis, wound healing, regeneration, and also in pathological conditions, such as …

Mechanical cues affect migration and invasion of cells from three different directions

CT Mierke - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Cell migration and invasion is a key driving factor for providing essential cellular functions
under physiological conditions or the malignant progression of tumors following downward …

A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration

N Hino, K Matsuda, Y Jikko, G Maryu, K Sakai… - Developmental Cell, 2022 - cell.com
Upon the initiation of collective cell migration, the cells at the free edge are specified as
leader cells; however, the mechanism underlying the leader cell specification remains …

Rac1 signaling: from intestinal homeostasis to colorectal cancer metastasis

L Kotelevets, E Chastre - Cancers, 2020 - mdpi.com
The small GTPase Rac1 has been implicated in a variety of dynamic cell biological
processes, including cell proliferation, cell survival, cell-cell contacts, epithelial …

Force-dependent binding of vinculin to α-catenin regulates cell–cell contact stability and collective cell behavior

R Seddiki, GHNS Narayana, PO Strale… - Molecular biology of …, 2018 - Am Soc Cell Biol
The shaping of a multicellular body and repair of adult tissues require fine-tuning of cell
adhesion, cell mechanics, and intercellular transmission of mechanical load. Adherens …

Mechanics of epithelial tissues during gap closure

S Begnaud, T Chen, D Delacour, RM Mège… - Current opinion in cell …, 2016 - Elsevier
The closure of gaps is crucial to maintaining epithelium integrity during developmental and
repair processes such as dorsal closure and wound healing. Depending on biochemical as …

Tension creates an endoreplication wavefront that leads regeneration of epicardial tissue

J Cao, J Wang, CP Jackman, AH Cox, MA Trembley… - Developmental cell, 2017 - cell.com
Mechanisms that control cell-cycle dynamics during tissue regeneration require elucidation.
Here we find in zebrafish that regeneration of the epicardium, the mesothelial covering of the …