The roles of tumor-and metastasis-promoting carcinoma-associated fibroblasts in human carcinomas
Carcinoma-associated fibroblasts (CAFs) constitute a substantial proportion of the non-
neoplastic mesenchymal cell compartment in various human tumors. These fibroblasts are …
neoplastic mesenchymal cell compartment in various human tumors. These fibroblasts are …
Atomic force microscopy for revealing micro/nanoscale mechanics in tumor metastasis: from single cells to microenvironmental cues
Mechanics are intrinsic properties which appears throughout the formation, development,
and aging processes of biological systems. Mechanics have been shown to play important …
and aging processes of biological systems. Mechanics have been shown to play important …
Chemical activation of the Piezo1 channel drives mesenchymal stem cell migration via inducing ATP release and activation of P2 receptor purinergic signaling
In this study, we examined the Ca2+-permeable Piezo1 channel, a newly identified
mechanosensing ion channel, in human dental pulp-derived mesenchymal stem cells …
mechanosensing ion channel, in human dental pulp-derived mesenchymal stem cells …
Collective curvature sensing and fluidity in three-dimensional multicellular systems
Collective cell migration is an essential process throughout the lives of multicellular
organisms, for example in embryonic development, wound healing and tumour metastasis …
organisms, for example in embryonic development, wound healing and tumour metastasis …
Microtubules in 3D cell motility
BP Bouchet, A Akhmanova - Journal of cell science, 2017 - journals.biologists.com
ABSTRACT Three-dimensional (3D) cell motility underlies essential processes, such as
embryonic development, tissue repair and immune surveillance, and is involved in cancer …
embryonic development, tissue repair and immune surveillance, and is involved in cancer …
[HTML][HTML] Store operated calcium entry in cell migration and cancer metastasis
AS Hammad, K Machaca - Cells, 2021 - mdpi.com
Ca2+ signaling is ubiquitous in eukaryotic cells and modulates many cellular events
including cell migration. Directional cell migration requires the polarization of both signaling …
including cell migration. Directional cell migration requires the polarization of both signaling …
The morphological and molecular mechanisms of epithelial/endothelial-to-mesenchymal transition and its involvement in atherosclerosis
M Wesseling, TR Sakkers, SCA De Jager… - Vascular …, 2018 - Elsevier
Cell transdifferentiation occurs during cardiovascular development or remodeling either as a
pathologic feature in the progression of disease or as a response to injury. Endothelial-to …
pathologic feature in the progression of disease or as a response to injury. Endothelial-to …
[HTML][HTML] Tubulin post-translational modifications: the elusive roles of acetylation
B Carmona, HS Marinho, CL Matos, S Nolasco… - Biology, 2023 - mdpi.com
Simple Summary Microtubules (MTs) are dynamic structures that compose part of the cell
cytoskeleton. They play important roles in various cellular functions, such as intracellular …
cytoskeleton. They play important roles in various cellular functions, such as intracellular …
Carcinogenesis and reactive oxygen species signaling: Interaction of the NADPH oxidase NOX1–5 and superoxide dismutase 1–3 signal transduction pathways
A Parascandolo, MO Laukkanen - Antioxidants & redox signaling, 2019 - liebertpub.com
Abstract Significance: Reduction/oxidation (redox) balance could be defined as an even
distribution of reduction and oxidation complementary processes and their reaction end …
distribution of reduction and oxidation complementary processes and their reaction end …
Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning
ER Summerbell, JK Mouw, JSK Bell, CM Knippler… - Science …, 2020 - science.org
Tumor heterogeneity drives disease progression, treatment resistance, and patient relapse,
yet remains largely underexplored in invasion and metastasis. Here, we investigated …
yet remains largely underexplored in invasion and metastasis. Here, we investigated …