Cell migration is a vital and dynamic process required for the development of multicellular
organisms and for immune system responses, tissue renewal and wound healing in adults. It …

During the growth of a cell collective, such as proliferating microbial colonies and epithelial
tissues, the local cell growth increases the local pressure, which in turn suppresses cell …

Septins as GTPases in the cytoskeleton, are linked to a broad spectrum of cellular functions,
including cell migration and the progression of hepatocellular carcinoma (HCC). However …

In this work, we show how the mechanical properties of the cellular microenvironment
modulate the growth of tumour spheroids. Based on the composition of the extracellular …

Tissue regeneration after injury requires coordinated regulation of stem cell activation,
division, and daughter cell differentiation, processes that are increasingly well understood in …

In this study, chaotic flows are used to biofabricate muscle tissue-like constructs that mimics
the hierarchical architecture of native skeletal muscle. Multi-layered and multi-material …

The a and b isoforms of keratin 6 (K6), a type II intermediate filament (IF) protein, are robustly
induced upon injury to interfollicular epidermis. We previously showed that complete loss of …

Light-sheet fluorescence microscopy (LSFM) has been present in cell biology laboratories
for quite some time, mainly as custom-made systems, with imaging applications ranging …

Collective cell migration is a highly complex process in which groups of cells move together.
A fundamental question is how cell ensembles can migrate efficiently. In some cases, the …

Collective cell migrations drive morphogenesis, wound healing, and cancer dissemination.
Cells located at the front are considered leaders while those behind them are defined …