Unravelling tumour heterogeneity by single-cell profiling of circulating tumour cells

L Keller, K Pantel - Nature Reviews Cancer, 2019 - nature.com
Single-cell technologies have contributed to unravelling tumour heterogeneity, now
considered a hallmark of cancer and one of the main causes of tumour resistance to cancer …

Early dissemination of circulating tumor cells: biological and clinical insights

F Chemi, S Mohan, T Guevara, A Clipson… - Frontiers in …, 2021 - frontiersin.org
Circulating tumor cells (CTCs) play a causal role in the development of metastasis, the major
cause of cancer-associated mortality worldwide. In the past decade, the development of …

Circulating tumour cells and outcome in non-metastatic colorectal cancer: a prospective study

U Bork, NN Rahbari, S Schölch, C Reissfelder… - British journal of …, 2015 - nature.com
Background: Circulating tumour cells (CTC) in the blood have been accepted as a
prognostic marker in patients with metastatic colorectal cancer (CRC). Only limited data exist …

Detection of circulating tumour cells enables early recurrence prediction in hepatocellular carcinoma patients undergoing liver transplantation

PX Wang, Y Xu, YF Sun, JW Cheng, KQ Zhou… - Liver …, 2021 - Wiley Online Library
Abstract Background & Aims Liver transplantation (LTx) is one of the most effective
treatments for hepatocellular carcinoma (HCC); however, tumour recurrence after LTx often …

Prognostic value of circulating tumor cells in patients with pancreatic cancer: a meta-analysis

L Han, W Chen, Q Zhao - Tumor Biology, 2014 - Springer
Increasing scientific evidences suggest that circulating tumor cells (CTC) in peripheral blood
may be a powerful predictor of survival in patients with pancreatic cancer. However, many …

[HTML][HTML] Prognostic value of circulating tumour cells in limited-stage small-cell lung cancer: analysis of the concurrent once-daily versus twice-daily radiotherapy …

RY Tay, F Fernández-Gutiérrez, V Foy, K Burns… - Annals of …, 2019 - Elsevier
Background The clinical significance of circulating tumour cells (CTCs) in limited-stage small-
cell lung cancer (LS-SCLC) is not well defined. We report a planned exploratory analysis of …

The prognostic impact of circulating tumor cells in subtypes of metastatic breast cancer

M Wallwiener, AD Hartkopf, I Baccelli… - Breast cancer research …, 2013 - Springer
The detection of circulating tumor cells (CTCs) in the peripheral blood of metastatic breast
cancer (MBC) patients is an independent marker of prognosis. This large prospective …

Clinical impact of circulating tumor cells in patients with localized prostate cancer

L Broncy, P Paterlini-Bréchot - Cells, 2019 - mdpi.com
The main issue concerning localized prostate cancers is the lack of a suitable marker which
could help patients' stratification at diagnosis and distinguish those with a benign disease …

Detection of circulating tumor cells in advanced head and neck cancer using the CellSearch system

AC Nichols, LE Lowes, CCT Szeto, J Basmaji… - Head & …, 2012 - Wiley Online Library
Background Early detection of circulating tumor cells (CTCs) offers the possibility of
improved outcome for patients with head and neck squamous cell cancer (HNSCC) …

Diagnostic technologies for circulating tumour cells and exosomes

H Shao, J Chung, D Issadore - Bioscience reports, 2016 - portlandpress.com
Circulating tumour cells (CTCs) and exosomes are promising circulating biomarkers. They
exist in easily accessible blood and carry large diversity of molecular information. As such …