[HTML][HTML] Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury

BY Gravesteijn, D Nieboer, A Ercole… - Journal of clinical …, 2020 - Elsevier
Objective We aimed to explore the added value of common machine learning (ML)
algorithms for prediction of outcome for moderate and severe traumatic brain injury. Study …

Traumatic brain injury in homeless and marginally housed individuals: a systematic review and meta-analysis

JL Stubbs, AE Thornton, JM Sevick… - The Lancet Public …, 2020 - thelancet.com
Background Homelessness is a global public health concern, and traumatic brain injury
(TBI) could represent an underappreciated factor in the health trajectories of homeless and …

Astaxanthin ameliorates oxidative stress and neuronal apoptosis via SIRT1/NRF2/Prx2/ASK1/p38 after traumatic brain injury in mice

XS Zhang, Y Lu, W Li, T Tao, L Peng… - British Journal of …, 2021 - Wiley Online Library
Background and Purpose Oxidative stress and neuronal apoptosis play key roles in
traumatic brain injury. We investigated the protective effects of astaxanthin against traumatic …

Pathological computed tomography features associated with adverse outcomes after mild traumatic brain injury: a TRACK-TBI study with external validation in …

EL Yuh, S Jain, X Sun, D Pisică, MH Harris… - JAMA …, 2021 - jamanetwork.com
Importance A head computed tomography (CT) with positive results for acute intracranial
hemorrhage is the gold-standard diagnostic biomarker for acute traumatic brain injury (TBI) …

Damaged brain accelerates bone healing by releasing small extracellular vesicles that target osteoprogenitors

W Xia, J Xie, Z Cai, X Liu, J Wen, ZK Cui, R Zhao… - Nature …, 2021 - nature.com
Clinical evidence has established that concomitant traumatic brain injury (TBI) accelerates
bone healing, but the underlying mechanism is unclear. This study shows that after TBI …

[HTML][HTML] Blood-based biomarkers of inflammation in mild traumatic brain injury: A systematic review

K Visser, M Koggel, J Blaauw, HJ van der Horn… - Neuroscience & …, 2022 - Elsevier
Abstract VISSER, K., M. Koggel, J. Blaauw, HJvd Horn, B. Jacobs, and Jvd Naalt. Blood
based biomarkers of inflammation in mild traumatic brain injury: A systematic review …

Dual roles of astrocytes in plasticity and reconstruction after traumatic brain injury

Y Zhou, A Shao, Y Yao, S Tu, Y Deng… - Cell Communication and …, 2020 - Springer
Traumatic brain injury (TBI) is one of the leading causes of fatality and disability worldwide.
Despite its high prevalence, effective treatment strategies for TBI are limited. Traumatic brain …

Surgery versus conservative treatment for traumatic acute subdural haematoma: a prospective, multicentre, observational, comparative effectiveness study

TA van Essen, HF Lingsma, D Pisică, RD Singh… - The lancet …, 2022 - thelancet.com
Background Despite being well established, acute surgery in traumatic acute subdural
haematoma is based on low-grade evidence. We aimed to compare the effectiveness of a …

Post-traumatic headache attributed to traumatic brain injury: classification, clinical characteristics, and treatment

H Ashina, AK Eigenbrodt, T Seifert, AJ Sinclair… - The Lancet …, 2021 - thelancet.com
Post-traumatic headache is a common sequela of traumatic brain injury and is classified as
a secondary headache disorder. In the past 10 years, considerable progress has been …

Ferroptosis: a critical player and potential therapeutic target in traumatic brain injury and spinal cord injury

QS Li, YJ Jia - Neural Regeneration Research, 2023 - journals.lww.com
Ferroptosis, a new non-necrotizing programmed cell death (PCD), is driven by iron-
dependent phospholipid peroxidation. Ferroptosis plays a key role in secondary traumatic …