Clinical translation of advanced colonic drug delivery technologies
Targeted drug delivery to the colon offers a myriad of benefits, including treatment of local
diseases, direct access to unique therapeutic targets and the potential for increasing …
diseases, direct access to unique therapeutic targets and the potential for increasing …
[HTML][HTML] Gut microbiota metabolites in major depressive disorder—Deep insights into their pathophysiological role and potential translational applications
MA Ortega, MA Alvarez-Mon, C García-Montero… - Metabolites, 2022 - mdpi.com
The gut microbiota is a complex and dynamic ecosystem essential for the proper functioning
of the organism, affecting the health and disease status of the individuals. There is …
of the organism, affecting the health and disease status of the individuals. There is …
[HTML][HTML] Metabolic cross-feeding in imbalanced diets allows gut microbes to improve reproduction and alter host behaviour
SF Henriques, DB Dhakan, L Serra… - Nature …, 2020 - nature.com
The impact of commensal bacteria on the host arises from complex microbial-diet-host
interactions. Mapping metabolic interactions in gut microbial communities is therefore key to …
interactions. Mapping metabolic interactions in gut microbial communities is therefore key to …
[HTML][HTML] Gut microbiome modulates Drosophila aggression through octopamine signaling
Y Jia, S Jin, K Hu, L Geng, C Han, R Kang… - Nature …, 2021 - nature.com
Gut microbiome profoundly affects many aspects of host physiology and behaviors. Here we
report that gut microbiome modulates aggressive behaviors in Drosophila. We found that …
report that gut microbiome modulates aggressive behaviors in Drosophila. We found that …
[HTML][HTML] Impact of cocoa flavanols on human health
MÁ Martin, S Ramos - Food and Chemical Toxicology, 2021 - Elsevier
Cocoa is a source of flavanols, and these phenolic compounds exert beneficial effects on
health and aging, and reduce the risk of suffering chronic diseases (cardiovascular …
health and aging, and reduce the risk of suffering chronic diseases (cardiovascular …
[HTML][HTML] Bifidobacterium longum counters the effects of obesity: Partial successful translation from rodent to human
Background The human gut microbiota has emerged as a key factor in the development of
obesity. Certain probiotic strains have shown anti-obesity effects. The objective of this study …
obesity. Certain probiotic strains have shown anti-obesity effects. The objective of this study …
Harnessing machine learning for development of microbiome therapeutics
The last twenty years of seminal microbiome research has uncovered microbiota's intrinsic
relationship with human health. Studies elucidating the relationship between an unbalanced …
relationship with human health. Studies elucidating the relationship between an unbalanced …
Identifying microbiome-mediated behaviour in wild vertebrates
Recent research in laboratory animals has illuminated how the vertebrate gut microbiome
can have diverse and powerful effects on the brain and behaviour. However, the ecological …
can have diverse and powerful effects on the brain and behaviour. However, the ecological …
Effect of cocoa and cocoa products on cognitive performance in young adults
MA Martín, L Goya, S de Pascual-Teresa - Nutrients, 2020 - mdpi.com
Increasing evidence support a beneficial role of cocoa and cocoa products on human
cognition, particularly in aging populations and patients at risk. However, thorough reviews …
cognition, particularly in aging populations and patients at risk. However, thorough reviews …
[HTML][HTML] Diet induces parallel changes to the gut microbiota and problem solving performance in a wild bird
GL Davidson, N Wiley, AC Cooke, CN Johnson… - Scientific reports, 2020 - nature.com
The microbial community in the gut is influenced by environmental factors, especially diet,
which can moderate host behaviour through the microbiome-gut-brain axis. However, the …
which can moderate host behaviour through the microbiome-gut-brain axis. However, the …