Next-generation sequencing technologies: An overview
T Hu, N Chitnis, D Monos, A Dinh - Human Immunology, 2021 - Elsevier
Since the days of Sanger sequencing, next-generation sequencing technologies have
significantly evolved to provide increased data output, efficiencies, and applications. These …
significantly evolved to provide increased data output, efficiencies, and applications. These …
Variants of uncertain significance in the era of high-throughput genome sequencing: a lesson from breast and ovary cancers
G Federici, S Soddu - Journal of Experimental & Clinical Cancer Research, 2020 - Springer
The promising expectations about personalized medicine have opened the path to routine
large-scale sequencing and increased the importance of genetic counseling for hereditary …
large-scale sequencing and increased the importance of genetic counseling for hereditary …
Fungal–metal interactions: A review of toxicity and homeostasis
JR Robinson, OS Isikhuemhen, FN Anike - Journal of Fungi, 2021 - mdpi.com
Metal nanoparticles used as antifungals have increased the occurrence of fungal–metal
interactions. However, there is a lack of knowledge about how these interactions cause …
interactions. However, there is a lack of knowledge about how these interactions cause …
Genome interpretation using in silico predictors of variant impact
Estimating the effects of variants found in disease driver genes opens the door to
personalized therapeutic opportunities. Clinical associations and laboratory experiments …
personalized therapeutic opportunities. Clinical associations and laboratory experiments …
[HTML][HTML] Pharmacogenomics in treatment of depression and psychosis: an update
Genetic factors can, to a certain extent, successfully predict the therapeutic effects,
metabolism, and adverse reactions of drugs. This research field, pharmacogenomics, is well …
metabolism, and adverse reactions of drugs. This research field, pharmacogenomics, is well …
Omics technologies in allergy and asthma research: An EAACI position paper
U Radzikowska, K Baerenfaller, JA Cornejo‐Garcia… - Allergy, 2022 - Wiley Online Library
Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …
several distinct complex endotypes. Both environmental and genetic factors can influence …
Next generation sequencing based forward genetic approaches for identification and mapping of causal mutations in crop plants: A comprehensive review
The recent advancements in forward genetics have expanded the applications of mutation
techniques in advanced genetics and genomics, ahead of direct use in breeding programs …
techniques in advanced genetics and genomics, ahead of direct use in breeding programs …
implementing whole genome sequencing (WGS) in clinical practice: advantages, challenges, and future perspectives
The integration of whole genome sequencing (WGS) into all aspects of modern medicine
represents the next step in the evolution of healthcare. Using this technology, scientists and …
represents the next step in the evolution of healthcare. Using this technology, scientists and …
Computational approaches for modeling and structural design of biological systems: A comprehensive review
E Gayathiri, P Prakash, P Kumaravel… - Progress in Biophysics …, 2023 - Elsevier
The convergence of biology and computational science has ushered in a revolutionary era,
revolutionizing our understanding of biological systems and providing novel solutions to …
revolutionizing our understanding of biological systems and providing novel solutions to …
Trimming and validation of Illumina short reads using trimmomatic, trinity assembly, and assessment of RNA-seq data
SO Sewe, G Silva, P Sicat, SE Seal… - … : Methods and protocols, 2022 - Springer
Next-generation sequencing (NGS) technologies can generate billions of reads in a single
sequencing run. However, with such high-throughput comes quality issues which have to be …
sequencing run. However, with such high-throughput comes quality issues which have to be …