Liquid biopsy in gastric cancer: predictive and prognostic biomarkers

Z Zhang, H Wu, W Chong, L Shang, C Jing, L Li - Cell death & disease, 2022 - nature.com
Gastric cancer (GC) is a high-incidence cancer worldwide. Most patients are diagnosed at
an advanced stage, by which time they have limited treatment options and poor prognosis …

Network approach in liquidomics landscape

D Santini, A Botticelli, A Galvano, M Iuliani… - Journal of Experimental …, 2023 - Springer
Tissue-based biopsy is the present main tool to explore the molecular landscape of cancer,
but it also has many limits to be frequently executed, being too invasive with the risk of side …

[HTML][HTML] Unintrusive multi-cancer detection by circulating cell-free DNA methylation sequencing (THUNDER): development and independent validation studies

Q Gao, YP Lin, BS Li, GQ Wang, LQ Dong, BY Shen… - Annals of …, 2023 - Elsevier
Background Early detection of cancer offers the opportunity to identify candidates when
curative treatments are achievable. The THUNDER study (THe UNintrusive Detection of …

[HTML][HTML] Long intragenic non-coding RNA p53-induced transcript (LINC-PINT) as a novel prognosis indicator and therapeutic target in cancer

T He, C Yuan, C Zhao - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Cancer involves complex etiology factors, multiple stages, and intricate gene mutations.
Long non-coding RNAs (lncRNAs) are implicated as molecular mechanisms underlying …

Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Y Deng, Z Sun, L Wang, M Wang, J Yang, G Li - Frontiers of medicine, 2021 - Springer
Cancer imposes a severe threat to people's health and lives, thus pressing a huge medical
and economic burden on individuals and communities. Therefore, early diagnosis of cancer …

Clinical trajectory of intraductal papillary mucinous neoplasms progressing to pancreatic carcinomas during long-term surveillance: a prospective series of 100 …

H Oyama, T Hamada, Y Nakai, M Tanaka… - Journal of …, 2023 - Springer
Background Trajectories of serological and morphological signatures have not been
documented in pancreatic carcinogenesis related to intraductal papillary mucinous …

CTC, ctDNA, and exosome in thyroid cancers: a review

W Wang, Z Zheng, J Lei - International journal of molecular sciences, 2023 - mdpi.com
Thyroid cancer has become more common in recent years all around the world. Many issues
still need to be urgently addressed in the diagnosis, treatment, and prognosis of thyroid …

Landscape of innovative methods for early diagnosis of gastric cancer: a systematic review

A Orășeanu, MC Brisc, OA Maghiar, H Popa, CM Brisc… - Diagnostics, 2023 - mdpi.com
From a global perspective, gastric cancer (GC) persists as a significant healthcare issue. In
the Western world, the majority of cases are discovered at late stages, when the treatment is …

A comprehensive review of the potential role of liquid biopsy as a diagnostic, prognostic, and predictive biomarker in pancreatic ductal adenocarcinoma

K Stosic, OA Senar, J Tarfouss, C Bouchart, J Navez… - Cells, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma is one of the most lethal malignant diseases, with a
mortality rate being close to incidence. Due to its heterogeneity and plasticity, as well as the …

[HTML][HTML] Fructose-Induced mTORC1 Activation Promotes Pancreatic Cancer Progression through Inhibition of Autophagy

Y Cui, J Tian, Z Wang, H Guo, H Zhang, Z Wang, H Liu… - Cancer Research, 2023 - AACR
Excessive fructose intake is associated with the occurrence, progression, and poor
prognosis of various tumors. A better understanding of the mechanisms underlying the …