[HTML][HTML] Role of Selenium in Pathogenesis and Treatment of the Autoimmune Diseases

E Rahmani, AM Fard, H Baghsheikhi, Z Hosseini… - Kindle, 2022 - preferpub.org
In vitro investigations have revealed that consumption of selenium can considerably
decrease the expression of IFN-g in Th1 cells. A low plasma selenium content has been …

Red Blood Cell Distribution Width: A Potential Inexpensive Marker for Disease Activity in Patients with Rheumatic Diseases; Scoping Review

M Alghamdi - Open Access Rheumatology: Research and Reviews, 2023 - Taylor & Francis
Background Rheumatic diseases encompass a diverse group of autoimmune disorders that
affect the joints and connective tissues. The red blood cell distribution width (RDW) has …

RGD-decorated nanoparticles: Therapeutic potential beyond cancer

SM Hosseinikhah, F Vahdat-Lasemi, L Farhoudi… - Journal of Drug Delivery …, 2024 - Elsevier
Abstract The RGD (Arg-Gly-Asp) peptide sequence is a cell adhesion motif found in many
extracellular matrix (ECM) proteins like fibronectin, laminin, and vitronectin. It is crucial in …

Engineered Exosomes loaded with triptolide: an innovative approach to enhance therapeutic efficacy in rheumatoid arthritis

X Jiang, L Shi, H Feng, Y Zhang, J Dong… - International …, 2024 - Elsevier
Objectives Exosomes are small, membrane-bound vesicles secreted by cells into the
extracellular environment. They play a crucial role in various biological processes, including …

Investigating the therapeutic potential of sinomenine in rheumatoid arthritis: anti-inflammatory, antioxidant, and immunomodulatory mechanisms

J Li, J Cao, Q Chen, D Liu, R Li - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
An autoimmune disease, rheumatoid arthritis (RA) is characterized by the onset of
inflammation and subsequent damage to the joints. Although several therapies are available …

A Review of Advances in Molecular Imaging of Rheumatoid Arthritis: From In Vitro to Clinic Applications Using Radiolabeled Targeting Vectors with Technetium-99m

M Ali, V Benfante, D Di Raimondo, R Laudicella… - Life, 2024 - mdpi.com
Rheumatoid arthritis (RA) is a systemic autoimmune disorder caused by inflammation of
cartilaginous diarthrodial joints that destroys joints and cartilage, resulting in synovitis and …

Zein-Derived Peptides from Corn Promote the Proliferation of C2C12 Myoblasts via Crosstalk of mTORC1 and mTORC2 Signaling Pathways

MS Amin, B Yu, D Wu, Y Lu, W Wu, J Wang, Y Zhang… - Foods, 2024 - mdpi.com
Dietary protein supplementation has emerged as a promising strategy in combating
sarcopenia. Furthermore, searching for alternatives of animal proteins has been a hot topic …

AI-driven covalent drug design strategies targeting main protease (mpro) against SARS-CoV-2: structural insights and molecular mechanisms

MH Haghir Ebrahim Abadi, A Ghasemlou… - Journal of …, 2024 - Taylor & Francis
The emergence of new SARS-CoV-2 variants has raised concerns about the effectiveness of
COVID-19 vaccines. To address this challenge, small-molecule antivirals have been …

Review on therapeutic potential of peptides: Advancements in synthesis methods, linear and cyclic peptides, and strategies for overcoming challenges

N Lalani, S Tivari, V Jain, Y Jadeja - Peptide Science, 2024 - Wiley Online Library
In the realm of therapeutic peptides, tremendous progress has been achieved in the last two
decades. The building block of peptides that is,'Amino Acid'has been modified by various …

Prodrug-based nanomedicines for rheumatoid arthritis

P Li, C Wang, H Huo, C Xu, H Sun, X Wang, L Wang… - Discover Nano, 2024 - Springer
Most antirheumatic drugs with high toxicity exhibit a narrow therapeutic window due to their
nonspecific distribution in the body, leading to undesirable side effects and reduced patient …