Alcohol use is increasing among adults 65 and older and the size of this population is
expanding rapidly. Aging is associated with systemic inflammation, sleep disturbances …

Excessive alcohol use curtails longevity by rendering intoxicated individuals vulnerable to
heightened risk from accidents, violence, and alcohol poisoning, and makes chronically …

During the last decade, substance use disorders (SUDs) have been increasingly recognized
as neuroinflammation-related brain diseases. Various types of abused drugs (cocaine …

Aldehyde dehydrogenase 2 (ALDH2) is an enzyme found in the mitochondrial matrix that
plays a central role in alcohol and aldehyde metabolism. A common ALDH2 polymorphism …

During the aging process our body becomes less well equipped to deal with cellular stress,
resulting in an increase in unrepaired damage. This causes varying degrees of impaired …

Genome-wide association studies (GWAS) of electroencephalographic endophenotypes for
alcohol use disorder (AUD) has identified noncoding polymorphisms within the KCNJ6 …

Alcohol consumption during pregnancy can significantly impact the brain development of the
fetus, leading to long-term cognitive and behavioral problems. However, the underlying …

Background We investigated a potential sex difference in the relationship between alcohol
consumption, brain age gap and cognitive function in older adults without cognitive …

This study was investigated to examine the neuroprotective effect of fermented Protaetia
brevitarsis larvae (FPB) in ethanol-induced-dementia mice. Consumption of FPB by mice …

Objective: Prenatal alcohol exposure causes fetal developmental abnormalities via
mitochondrial dysfunction, reactive oxygen species (ROS) formation, and oxidative stress …