Papillary thyroid cancer—Aggressive variants and impact on management: A narrative review

A Coca-Pelaz, JP Shah, JC Hernandez-Prera… - Advances in …, 2020 - Springer
Introduction Aggressive variants of papillary thyroid cancer (PTC) have been described with
increasing frequency. These variants include diffuse sclerosing variant, tall cell variant …

Pathogenetic mechanisms in thyroid follicular-cell neoplasia

T Kondo, S Ezzat, SL Asa - Nature Reviews Cancer, 2006 - nature.com
Thyroid cancer is one of the few malignancies that are increasing in incidence. Recent
advances have improved our understanding of its pathogenesis; these include the …

[HTML][HTML] PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients

F Perrone, A Lampis, M Orsenigo, M Di Bartolomeo… - Annals of oncology, 2009 - Elsevier
Background: It has been reported that KRAS mutations (and to a lesser extent KRAS
mutations with the BRAF V600E mutation) negatively affect response to anti-epidermal …

Association of BRAF V600E mutation with poor clinicopathological outcomes in 500 consecutive cases of papillary thyroid carcinoma

C Lupi, R Giannini, C Ugolini, A Proietti… - The Journal of …, 2007 - academic.oup.com
Context: Because very few studies have examined the correlation between BRAF mutations
and clinicopathological features of papillary thyroid carcinoma (PTC), we analyzed here a …

Special types of thyroid carcinoma

ZW Baloch, VA LiVolsi - Histopathology, 2018 - Wiley Online Library
This article reviews the small percentage of thyroid tumours that are not classified as classic
papillary thyroid carcinoma, follicular thyroid carcinoma, and medullary thyroid carcinoma. It …

Correlation between the BRAF V600E Mutation and Tumor Invasiveness in Papillary Thyroid Carcinomas Smaller than 20 Millimeters: Analysis of 1060 Cases

F Basolo, L Torregrossa, R Giannini… - The Journal of …, 2010 - academic.oup.com
Context: Evaluation of the degree of neoplastic infiltration beyond the thyroid capsule
remains a unique parameter that can be evaluated by histopathological examination to label …

Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma

O Koperek, C Kornauth, D Capper… - The American journal …, 2012 - journals.lww.com
The V600E mutation of the B-type Raf kinase (BRAF) gene is a common event in papillary
thyroid carcinoma (PTC) and seems to play a key role in the development and progression …

Aggressive variants of follicular cell-derived thyroid carcinoma: an overview

C Pizzimenti, V Fiorentino, A Ieni, M Martini, G Tuccari… - Endocrine, 2022 - Springer
Purpose The incidence of thyroid carcinoma has increased globally in the past years.
Papillary thyroid carcinoma (PTC) is the most frequent neoplasm of the thyroid gland …

Mutation Analysis of BRAF, MEK1 and MEK2 in 15 Ovarian Cancer Cell Lines: Implications for Therapy

AL Estep, C Palmer, F McCormick, KA Rauen - PloS one, 2007 - journals.plos.org
Background Among gynecologic cancers, ovarian cancer is the second most common and
has the highest death rate. Cancer is a genetic disorder and arises due to the accumulation …

Molecular Pathology of Non-familial Follicular Epithelial–Derived Thyroid Cancer in Adults: From RAS/BRAF-like Tumor Designations to Molecular Risk Stratification

P Soares, AA Povoa, M Melo, J Vinagre, V Maximo… - Endocrine …, 2021 - Springer
This review addresses the impact of molecular alterations on the diagnosis and prognosis of
differentiated thyroid carcinoma (DTC), including papillary, follicular, and well-differentiated …