Inflammation is essential in the initial development and progression of many cardiovascular
diseases involving innate and adaptive immune responses. The role of CD4+ CD25+ …

Immune-related adverse events, particularly severe toxicities such as myocarditis, are major
challenges to the utility of immune checkpoint inhibitors (ICIs) in anticancer therapy. The …

Heart failure is a global problem with high hospitalization and mortality rates. Inflammation
and immune dysfunction are involved in this disease. Owing to their unique function …

Background: Inflammatory responses play a critical role in left ventricular remodeling after
myocardial infarction (MI). Tolerogenic dendritic cells (tDCs) can modulate immune …

The stimulator of interferon genes (STING) is a critical protein in the activation of the immune
system in response to DNA. It can participate the inflammatory response process by …

Accumulating evidence reveals involvement of T lymphocytes and adaptive immunity in the
chronic inflammation associated with infectious and noninfectious diseases of the heart …

Autoimmunity significantly contributes to the pathogenesis of myocarditis, underscored by its
increased frequency in autoimmune diseases such as systemic lupus erythematosus and …

Myocarditis is an inflammatory cardiac disease characterized by the destruction of
myocardial cells, infiltration of interstitial inflammatory cells, and fibrosis, and is becoming a …

Dendritic cells (DCs) play a key role in the activation of the immune response against
pathogens, as well as in the modulation of peripheral tolerance to self-antigens (Ags) …

Dendritic cells (DCs) are the most potent professional antigen-presenting cells (APCs) and
inducers of T cell-mediated immunity. Although DCs play a central role in promoting …