Hydroxychloroquine in systemic lupus erythematosus (SLE)

C Ponticelli, G Moroni - Expert opinion on drug safety, 2017 - Taylor & Francis
Introduction: Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that
accumulates in lysosomes where it inhibits some important functions by increasing the pH …

Old and new calcineurin inhibitors in lupus nephritis

C Ponticelli, F Reggiani, G Moroni - Journal of Clinical Medicine, 2021 - mdpi.com
Calcineurin inhibitors (CNIs) are drugs that inhibit calcineurin, a key phosphatase that
dephosphorylates a transcription factor called the nuclear factor of activated T cells (NFAT) …

Systemic lupus erythematosus and pregnancy: the challenge of improving antenatal care and outcomes

DEA Pastore, ML Costa, FG Surita - Lupus, 2019 - journals.sagepub.com
Objectives The objective of this article is to describe maternal and perinatal outcomes in
women with systemic lupus erythematosus (SLE) followed in a high-risk prenatal outpatient …

Antinuclear antibodies positivity in women in reproductive age: from infertility to adverse obstetrical outcomes–a meta-analysis

C Ticconi, A Inversetti, E Logruosso, M Ghio… - Journal of Reproductive …, 2023 - Elsevier
This systematic review and meta-analysis were designed to identify possible correlations
between isolated serum antinuclear antibody (ANA) and (i) infertility in the context of in-vitro …

Lupus low disease activity state achievement is important for reducing adverse outcomes in pregnant patients with systemic lupus erythematosus

JW Kim, JY Jung, HA Kim, JI Yang, DW Kwak… - The Journal of …, 2021 - jrheum.org
Objective This study aimed to examine the frequency and risk factors of complications during
pregnancy in women with systemic lupus erythematosus (SLE). Methods The medical …

Risk of miscarriage in women with chronic diseases in Norway: A registry linkage study

MC Magnus, NH Morken, KA Wensaas, AJ Wilcox… - PLoS …, 2021 - journals.plos.org
Background Increased risk of miscarriage has been reported for women with specific chronic
health conditions. A broader investigation of chronic diseases and miscarriage risk may …

Mediation of adverse pregnancy outcomes in autoimmune conditions by pregnancy complications: a mediation analysis of autoimmune conditions and adverse …

G Bandoli, N Singh, J Strouse, RJ Baer… - Arthritis Care & …, 2020 - Wiley Online Library
Objective Autoimmune conditions are associated with an increased risk of adverse
pregnancy complications and outcomes, suggesting that pregnancy complications may …

Effect of hydroxychloroquine on lupus activity, preeclampsia and intrauterine growth restriction in pregnant women with systemic lupus erythematosus and/or …

Z Hu, R Gao, W Huang, H Wang, L Qin - Journal of Clinical Medicine, 2023 - mdpi.com
Background: Hydroxychloroquine (HCQ) has been used in the treatment of systematic lupus
erythematosus (SLE) and antiphospholipid syndrome (APS), but its effect on lupus activity …

Challenges of caring for transgender and gender diverse patients with rheumatic disease: presentation of seven patients and review of the literature

K Mathias, L Mathias, A Amarnani… - Current Opinion in …, 2023 - journals.lww.com
Challenges of caring for transgender and gender diverse pati... : Current Opinion in
Rheumatology Challenges of caring for transgender and gender diverse patients with …

Contraception in chronic kidney disease: a best practice position statement by the Kidney and Pregnancy Group of the Italian Society of Nephrology

R Attini, G Cabiddu, B Montersino, L Gammaro… - Journal of …, 2020 - Springer
Even though fertility is reduced, conception and delivery are possible in all stages of CKD.
While successful planned pregnancies are increasing, an unwanted pregnancy may have …